The Domain Name System of the Internet consists of a set of top-level domains which constitute the root domain of the hierarchical name space and database. In the growth of the Internet, it became desirable to expand the set of initially six generic top-level domains in 1984. As a result new top-level domain names have been proposed for implementation by ICANN. Such proposals included a variety of models ranging from adoption of policies for unrestricted gTLDs that could be registered by anyone for any purpose, to chartered gTLDs for specialized uses by specialized organizations. In October 2000, ICANN published a list of proposals for top-level domain strings it had received.
Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex.
Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the head module, and components of this submodule act together in a gene-regulatory programme to suppress smooth muscle cell differentiation. Thus, mammalian Mediator subunit Med28 functions as a repressor of smooth muscle-cell differentiation, which could have implications for disorders associated with abnormalities in smooth muscle cell growth and differentiation, including atherosclerosis, asthma, hypertension, and smooth muscle tumours.
MED28 has been shown to interact with Merlin,Grb2 and MED26.
This article incorporates text from the public domain Pfam and InterPro IPR021640
Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.
This family of proteins represent the transcriptional mediator protein subunit 6 that is required for activation of many RNA polymerase II promoters and which are conserved from yeast to humans.
MED6 has been shown to interact with:
This article incorporates text from the public domain Pfam and InterPro IPR007018
Europa (AK-81) was never commissioned and thus never bore the USS designation.
The ship was laid down 2 March 1942 as MV William Lester, a Maritime Commission type (N3-M-A1) hull, under Maritime Commission contract (MC hull 464), at the Penn-Jersey Shipbuilding Company of Camden, New Jersey and launched 7 December 1942. Assigned to the Navy as Europa (AK-81), named for Europa, the smallest of the Galilean moons of planet Jupiter, scheduled to become an Enceladus-class cargo ship. She was delivered to the Navy uncompleted 24 November 1943; transferred the next day, 25 November 1943, to the United States Army; stricken from Navy lists 6 December 1943.
The ship, renamed Thomas F. Farrell Jr., after an Engineering officer killed 25 February 1944 at Anzio, began conversion in December, 1943 to an Engineer Port Repair ship manned by a military crew under the U.S. Army Corps of Engineers. The ship did not complete conversion until 30 April 1944 and did not sail for Europe until late summer. The ship was one of the port repair ships making it to Europe in time to assist in the restoration of ports.
Europa is a stream of consciousness novel by Tim Parks, first published in 1997. It was shortlisted for the Booker Prize in that year, losing out to Arundhati Roy's The God of Small Things.
Jerry Marlow is a neurotic obsessive whose first-person narration describes a coach trip he and several colleagues take to Strasbourg in order to petition the European Parliament for improved working conditions for foreign university teachers working in Italy. While observing the idiosyncrasies of his colleagues, Marlow constantly revisits personal anxieties about relationships with his ex-lover, his wife, and his daughter. In a surprising tragicomic ending, Marlow realises both success and failure, all somehow entwined and impossible to separate.