ESR

ESR may refer to:

Organizations

Greek National Council for Radio and Television (Ethnikó Simvúlio Radhiotileórasis)

Institute of Environmental Science and Research, a New Zealand scientific institute

Earlham School of Religion, at Earlham College in Richmond, Indiana, US

E.S.R., Inc., a former American toy manufacturer

ESR Rīga, a Soviet Latvian football club, active from 1966 to 1991

ESR Technology, a UK company

European Society of Radiology

Science

EISCAT Svalbard radar, UHF-band radar at Longyearbyen, Norway

Electron spin resonance, a technique used in chemical spectroscopy to identify unpaired electrons and free radicals

Erythrocyte sedimentation rate, the rate at which red blood cells sediment

Estrogen receptor, a group of proteins

Technology

Electro-slag remelting, an alloy remelting and refining process

Electronic Staff Record, a human resources and payroll system of the UK National Health Service

Equivalent series resistance, the resistive parts of the impedance of certain electrical components

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/ESR

Estrogen receptor beta

Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen. In humans, ER-β is encoded by the ESR2 gene.

Function

ER-β is a member of the family of estrogen receptors and the superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17-β-estradiol, estriol or related ligands, the encoded protein forms homo-dimers or hetero-dimers with estrogen receptor α that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Estrogen_receptor_beta

Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen. In humans, ERα is encoded by the gene ESR1 (EStrogen Receptor 1).

Structure

The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription.Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less variability.