Ercole II d'Este (5 April 1508 – 3 October 1559) was Duke of Ferrara, Modena and Reggio from 1534 to 1559. He was the eldest son of Alfonso I d'Este and Lucrezia Borgia.
Through his mother, Ercole was a grandson of Pope Alexander VI, nephew of Cesare Borgia, and cousin of Saint Francis Borgia. Through his father, he was nephew of both Isabella d'Este, "the First Lady of the Renaissance", and Cardinal Ippolito d'Este. His siblings included Ippolito II, Archbishop of Milan and later Cardinal, nun Leonora, and Francesco, Marchese di Massalombarda. His half-siblings included Rodrigo Borgia of Aragon, Lucrezia’s son by Alfonso of Aragon, Duke of Bisceglie, and perhaps Giovanni Borgia, the “infans Romanus”.
In April 1528, he married Renée of France, the second daughter of Louis XII, King of France, and Anne of Brittany. Renée received from Francis I of France an ample dowry and annuity. Thus the court she assembled about her in Ferrara corresponded to the tradition which the cultivation of science and art implicitly required, including scholars like Bernardo Tasso and Fulvio Pellegrini Morato. Their first child, Anna, born in 1531, who was married to Francis, Duke of Guise, was followed by Alfonso in 1533; Lucrezia in 1535, who was married to the Duke of Urbino Francesco Maria II della Rovere; and later Eleonora and Luigi, whose education she carefully directed.
The House of Este ([ˈɛste] Italian: Casa d'Este, originally House of Welf-Este) is a European princely dynasty. It is one of the most ancient noble dynasties in Europe.
The elder branch of the House of Este included the dukes of Brunswick and Lüneburg (1208–1918) and produced Britain's Hanoverian monarchs and one Emperor of Russia (Ivan VI).
The younger branch of the House of Este included rulers of Ferrara (1240–1597), and Modena and Reggio (1288–1796).
Edward Gibbon said the family originated from the Roman Attii family, which migrated from Rome to Este to defend Italy against the Ostrogoths. However, there is little evidence to support this hypothesis. The names of the early members of the family indicate that a Frankish origin is much more likely. The first known member of the house was Margrave Adalbert of Mainz, known only as father of Oberto I, Count palatine of Italy, who died around 975. Oberto's grandson, Albert Azzo II, Margrave of Milan (996–1097) built a castle at Este, near Padua, and named himself after it. He had three sons from two marriages, two of whom became the ancestors of the two branches of the family: