Eomesodermin

Eomesodermin also known as T-box brain protein 2 (TBR2) is a protein that in humans is encoded by the EOMES gene.

This gene encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Eomesodermin itself controls regulation of radial glia, amongst other things. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.

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Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.