Moca

Moca or MOCA may refer to:

Places

Science and technology

Museums

Other uses

Moca, Espaillat

Moca is the capital of Espaillat province, in the Cibao region of the Dominican Republic, and it is the tenth-largest city of that country. Moca is located 11 miles/18 kilometers away from the country’s second city, Santiago. Known as "La Villa Heroica" (Village of Heroes) due to the amount of men and women from Moca who have played a major role in the Dominican Republic's history in bringing down two dictators, Ulises Heureaux and Rafael Trujillo, and bringing democracy back to the country.

Moca is home to the Corazon Sagrado de Jesus ("Sacred Heart of Jesus") Cathedral. All its pane glass windows were originally brought from Italy depicting the apostles and Jesus' path to the crucifixion. Agriculture forms the primary livelihood of the inhabitants. Plantain and yucca are main crops. Most crops are harvested by hand.

Moca is also recognized for its strong political up bringing. Former dictator Rafael Trujillo owned a house in Moca. In fact, the house is located a few blocks from the church Sagrado Corazon De Jesus (picture above).

Dock3

Dock3 (Dedicator of cytokinesis 3), also known as MOCA (modifier of cell adhesion) and PBP (presenilin-binding protein), is a large (~180 kDa) protein involved in intracellular signalling networks. It is a member of the DOCK-B subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock3 specifically activates the small G protein Rac.

Discovery

Dock3 was originally discovered in a screen for proteins that bind presenilin (a transmembrane protein which is mutated in early onset Alzheimer's disease). Dock3 is specifically expressed in neurones (primarily in the cerebral cortex and hippocampus).

Structure and function

Dock3 is part of a large class of proteins (GEFs) which contribute to cellular signalling events by activating small G proteins. In their resting state G proteins are bound to Guanosine diphosphate (GDP) and their activation requires the dissociation of GDP and binding of guanosine triphosphate (GTP). GEFs activate G proteins by promoting this nucleotide exchange.

Embrace

Embrace may refer to:

Music

Embrace (non-profit)

Embrace is a non profit organization providing low-cost incubators to prevent neonatal deaths in rural areas in developing countries. The organization was developed in 2008 during the multidisciplinary Entrepreneurial Design For Extreme Affordability course at Stanford University by group members Jane Chen, Linus Liang, Rahul Panicker, Razmig Hovaghimian, and Naganand Murty.

Incubator

The Embrace infant warmer is a low-cost solution that maintains premature and low-birth-weight babies’ body temperature. The infant warmer is portable, safe, reusable, and requires only intermittent access to electricity. Each baby warmer is priced at approximately $25. The Embrace development team won the fellowship at the Echoing Green competition in 2008 for this concept. Embrace also won the 2007-2008 Business Association of Stanford Entrepreneurial Students Social E-Challenge competition grand prize. At a ceremony at BAFTA in London on December 3rd 2013 Jane Chen, Linus Liang, Naganand Murty and Rahul Panicker won an innovation award from the Economist. Embrace also partners with UniversalGiving to raise fund for its project, which is to provide the Embrace infant warmers in Kabul, Afghanistan.

Embrace (Boom Boom Satellites album)

Embrace is the eighth studio album by Japanese electronic/rock duo Boom Boom Satellites. Released on January 9, 2013, Embrace serves as the band's 15th anniversary release. Songs on the album include their single "Broken Mirror" and the song "Drifter", which was used in Sony's Xperia commercials. The album will also be sold in a deluxe edition that contains a DVD and a USB flash drive. JPU Records released the album in the UK, Europe and Russia on 2 September 2013. The CD version from JPU Records contained an exclusive remix of Snow.

To support the album, BBS are going on both a short pre-release party tour at Club Quattro locations in Shibuya, Tokyo; Umeda, Osaka; and Nagoya, Aichi Prefecture; and on a national tour following the album's release. The band will also livestream the final mastering of the album at New York City's Sterling Sound studio on Nico Nico Douga. The first promotional single from Embrace was a cover of the Beatles' "Helter Skelter", the duo's first ever cover song. This was followed by the release of another digital single of the track "Nine". In addition, album versions of previous promotional singles "Another Perfect Day" (released as a "Movie Edit") and "Drifter" (released as a "test run") are included on Embrace.