Egis

Egis or EGIS has a variety of meanings, including:

EGIS-12,233

EGIS-12,233 is a drug with applications in scientific research, acting as a potent and selective antagonist for both the 5-HT₆ and 5-HT₇ serotonin receptor subtypes, with good selectivity over other receptors. It has been shown to increase dopamine release in cochlear tissue, suggesting a role for the 5-HT₆ and 5-HT₇ receptors in regulation of the hearing system.

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EGIS-7625

EGIS-7625 is a selective and competitive 5-HT_2B receptor antagonist. It is experimentally proven to be directly associated with smooth stomach muscle construction of white rats in vivo, and variably effective in provoking a similar response in in vitro human stomach cells. In high blood concentrations, it causes mild constriction of rabbit pulmonary arteries.

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