EVT

EVT is a three letter acronym for:

  • Earned Value Technique, a project management technique
  • Electrically Variable Transmission (EVT) in the Transmission_(mechanics)#Electric_variable page
  • Emergency Vehicle Technician, a technician who has been certified by the Emergency Vehicle Technician Certification Commission
  • Engineering validation test, the first in a sequence of new-product development stages
  • Enterprise Value Tax, a putative tax on the disposal of a business
  • Environment Verification Testing, the testing of a new environment into an existing network (such as SIT, DEV, PR or UAT)
  • Equiviscous temperature, the temperature at which bitumen attains the proper viscosity for application.
  • Estill Voice Training, a programme for developing vocal skills
  • European Vale Tudo, a mixed martial arts promotion based in Sweden
  • Expectancy Violations Theory, a theory in the study of communications.
  • The Extreme value theorem, a theorem in calculus
  • Extreme value theory, a branch of statistics
  • EVT-201

    EVT-201 is a benzodiazepine derivative drug and partial positive allosteric modulator of the benzodiazepine site of the GABAA receptor. It has 2–4-fold higher functional affinity for the α1 subunit relative to the α2, α3, and α5 subunits and significantly less intrinsic activity in comparison to currently-marketed benzodiazepines and the Z-drugs. Despite the lower efficacy, EVT-201 still shows effectiveness in the treatment of insomnia, and it is thought that the lower efficacy may result in fewer side effects, such as motor incoordination. The drug was originally developed by Roche, based on preclinical data, as a non-sedating anxiolytic, but was found to produce sedation in humans in phase I clinical trials. For this reason, it was subsequently licensed to Evotec, which is now developing it for the treatment of insomnia. As of 2007, EVT-201 has completed phase II clinical trials for this indication, with positive findings reported. As of August, 2015, Phase II development is ongoing in China.

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