ETF

ETF may refer to:

Organisations

Technical terms

Eukaryotic release factors

Eukaryotic translation termination factor 1 (eRF1), also known asTB3-1, is a protein that in humans is encoded by the ETF1 gene.

In eukaryotes, this is the only release factor (eRF) which recognizes all three stop codons. The overall process of termination is similar in prokaryotes, but in the latter 3 separate release factors exist, RF1, RF2 and RF3.

Function

Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA, a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs, which are not codon specific and do not recognize codons, stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes, both class 1 RFs, RF1 and RF2, recognize UAA; however, UAG and UGA are decoded specifically by RF1 and RF2, respectively. In eukaryotes, eRF1, or ETF1, the functional counterpart of RF1 and RF2, functions as an omnipotent RF, decoding all 3 stop codons.

Escape the Fate

Escape the Fate is an American rock band from Las Vegas, Nevada, formed in 2005 and originally from Pahrump, Nevada. They are signed to Eleven Seven Music. The group consists of Robert Ortiz (drummer), Craig Mabbitt (lead vocalist), TJ Bell (rhythm guitarist and vocalist), Kevin "Thrasher" Gruft (lead guitarist) and touring musician Max Georgiev (bassist). As of 2013, Ortiz is the last founding member in the current line up of the group.

They have released three EPs and four full-length studio albums. Dying Is Your Latest Fashion was the band's first album and only album with the vocalist Ronnie Radke. This War Is Ours was released on October 21, 2008. This album departed from the band's earlier emo, darker sound, to a more hard rock, mainstream sound. Less screamed vocals are used and the album has a varied, mixed sound changing from track to track. It is the first Escape the Fate album to with the former Blessthefall singer Craig Mabbitt. The album debuted at No. 35 on the Billboard 200, selling 13,000 copies in the first week. Their third studio album, Escape the Fate, was released worldwide on November 2, 2010. It was the band's only album released on DGC/Interscope following their departure with Epitaph. The album charted at No. 25 on the Billboard 200, No. 1 on Hard Rock Albums, No. 4 on Rock Albums, No. 3 on Alternative and Independent charts and No. 18 on the Digital Albums Chart. The album is heavier than the previous album and has a darker sound. On release, the album received generally positive reviews, and is Escape the Fate's most successful album to date. It is the band's last release with bass guitarist Max Green. Their fourth album, Ungrateful, was released on May 14, 2013, by Eleven Seven Music, and charted at No. 27 on the Billboard 200, with 17,000 copies sold in its first week.