E4F1
Transcription factor E4F1 is a protein that in humans is encoded by the E4F1 gene.
Function
The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.
Interactions
E4F1 has been shown to interact with:
References
Further reading
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Podcasts:
I. F. Y.
by: VaderOriginally performed by Depeche Mode
Music: Depeche Mode / Lyrics: Piotr Wiwczarek
I feel you
Your son is dead
I feel you
Within my mind
You're fearing me
Still fearing me
My kingdom comes
You tried to do
To lead me through eternity
But this is the morning of our law
And this is the dawning of our law
I hear you
Your fadin' voice
I feel you
Die on the cross
The joy it brings
When heaven burns
Your golden gates
Don't try to do
'Cause I'll kill you eternally
This is the dawning of fallen one
And this is is the fall of your nailed son
I kill you
Your holy soul
And I kill more
I feel you
Your suffer-son
My kingdom comes
I feel you
Each move you make
I feel you
What for you wait
Where angels sing
I spread my wings
See my rebirth
I'll take you down
To glory's throne
Don't ask me... why?