TCF3
Transcription factor 3 (E2A immunoglobulin enhancer-binding factors E12/E47), also known as TCF3, is a protein that in humans is encoded by the TCF3 gene. TCF3 has been shown to directly enhance Hes1 (a well-known target of Notch signaling) expression.
Function
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development.
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Out Of Control
by: U2Monday morning
Eighteen years of dawning
I say how long
You say how long
It was one dull morning
Woke the world with bawling
I was so sad (so sad)
It was so bad
I was of a feeling it was out of control
I had the opinion it was out of control
Boys and Girls
Go to the school and girls
They make children
Not like this one
I was of a feeling it was out of control
I had the opinion it was out of control
I was of a feeling it was out of control
I had the opinion it was out of control
(Out of control)
I fought fate
There's blood on the garden gate
The man said childhood
It's in his childhood
One day I'll die
The choice will not be mine
Will it be too late
You can't fight it
I was of a feeling it was out of control