The E1cB elimination reaction is a type of elimination reaction which occurs under basic conditions, where a particularly poor leaving group (such as -OH or -OR) and an acidic hydrogen eliminate to form an additional bond. E1cB is a two-step process. First, a base abstracts the most acidic proton to generate a stabilized anion. The lone pair of electrons on the anion then moves to the neighboring atom, thus expelling the leaving group and forming double or triple bond. The name of the mechanism - E1cB - stands for Elimination Unimolecular conjugate Base. Elimination refers to the fact that the mechanism is an elimination reaction and will lose two substituents. Unimolecular refers to the fact that the rate-determining step of this reaction only involves one molecular entity. Finally, conjugate base refers to the formation of the carbanion intermediate, which is the conjugate base of the starting material.
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With a honky tonky monkey shine
When you hold my hand I'm a pre-historic man, I go ape!