Drug

A drug is any substance other than food, that when inhaled, injected, smoked, consumed, absorbed via a patch on the skin or dissolved under the tongue causes a physiological change in the body.

In pharmacology, a pharmaceutical drug or medicine, is a chemical substance used to treat, cure, prevent, diagnose a disease or promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders.

Pharmaceutical drugs are often classified into drug classes—groups of related drugs that have similar chemical structures, the same mechanism of action (binding to the same biological target), a related mode of action, and that are used to treat the same disease. The Anatomical Therapeutic Chemical Classification System (ATC), the most widely used drug classification system, assigns drugs a unique ATC code, which is an alphanumeric code that assigns it to specific drug classes within the ATC system. Another major classification system is the Biopharmaceutics Classification System. This classifies drugs according to their solubility and permeability or absorption properties.

Shithead (card game)

Shithead (also known as Karma, Palace, Shed, Three Card Game and by many other names) is a card game similar to the Finnish game Paskahousu. In the game the object is to lose all of one's cards, with the last player to do so being the "shithead", who must deal the next game and may be subject to some minor forfeit of the group's choice, such as fetching the next round of drinks.

The game, and variations of it, is popular in many countries amongst backpackers, and as a result is widespread. Although the basic structure of the game generally remains constant there are often regional variations of the game's original rules.

Rules

There are many variations of the rules, and there is no universally accepted set. A common set of rules is listed here.

Setup

From a standard, shuffled deck of 52 cards, each player is dealt three face-down cards in a row. Players are not allowed to see or change these cards. On top of the face-down cards, they are dealt the same number of face-up cards. Three cards are again dealt to each player (face down), and this becomes the player's hand.

Drugs (journal)

Drugs is a peer-reviewed medical journal published by Adis International (Springer Science + Business Media) that covers topics in drugs and therapeutics. Besides research articles, the journal also publishes "Adis Drug Evaluations and Profiles", evidence-based, single-agent reviews.

Abstracting and indexing

Drugs is abstracted and indexed in:

According to the Journal Citation Reports it received an impact factor of 4.343, ranking it 9th out of 87 journals in the category "Toxicology" and ranking it 32nd out of 254 journals in the category "Pharmacology & Pharmacy"

References

External links

RPA

RPA may refer to:

In Information Technology:

In government:

RPA (TV series)

RPA is an Australian reality television show that is filmed at Royal Prince Alfred Hospital and shows the everyday workings of this major hospital in Sydney, Australia. Premiering in 1995, the programme is based on the British series Jimmy's which was filmed at St James's University Hospital in Leeds.

Format

For the majority of its thirteen-year run, each episode of RPA has run for half an hour. However, its initial 2007 run was broadcast in combined hour-long episodes, and its return later in the year saw it assume a permanent one-hour timeslot. Operations are recorded on camera and the doctors provide commentary as they operate on patients.

A new RPA: Where Are They Now series, begun in 2007, runs for half an hour. It profiles the lives of patients who have previously appeared on RPA, recapping the original stories and showing follow-ups on the patients' lives or deaths following their initial appearance on the programme. Both series are narrated by Max Cullen.

A brand-new series of the medical/observational series aired on the Nine Network in October 2008. Max Cullen will continue to narrate. The program returned in February 2009 for another brand new series.

RPA (Rubin Postaer and Associates)

RPA is an American advertising and marketing agency headquartered in Santa Monica, California. It was founded in 1986 by Gerry Rubin and Larry Postaer and currently employs approximately 500 associates. RPA has regional offices in Portland, Denver, Dallas, Chicago, Atlanta, Boston and Moorestown.

Services include broadcast and print creative development, TV, print and radio planning and buying, Web development and interactive marketing, e-mail and mobile marketing, search marketing, strategic planning and research, DRTV, collateral development, sales training and event marketing.

RPA billed in excess of $1 billion in 2007. RPA ranked fifth in revenue among U.S. independent advertising agencies in 2006, at $105.2 million (up 5.7% from 2005).

Clients

Recent awards and recognitions