Dronedarone
Dronedarone (development codename SR33589 and marketed as Multaq) is a drug by Sanofi-Aventis, mainly for the indication of cardiac arrhythmias. It was approved by the FDA on July 2, 2009. It was recommended as an alternative to amiodarone for the treatment of atrial fibrillation and atrial flutter in people whose hearts have either returned to normal rhythm or who undergo drug therapy or electric shock treatment i.e. direct current cardioversion (DCCV) to maintain normal rhythm. It is a class III antiarrhythmic drug. In the United States, the FDA approved label includes a claim for reducing hospitalization, but not for reducing mortality, as a reduction in mortality was not demonstrated in the clinical development program. A trial of the drug in heart failure was stopped as an interim analysis showed a possible increase in heart failure deaths, in patients with moderate to severe CHF.
The U.S. label for dronedarone includes a boxed warning, stating that dronedarone is contraindicated in patients with NYHA Class IV heart failure, with NYHA Class II–III heart failure with a recent decompensation requiring hospitalization or referral to a specialized heart failure clinic, or with permanent atrial fibrillation." Dronedarone is also associated with rare case of severe liver damage, including liver failure.
Podcasts:
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by Trina
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by Anneli Drecker
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by Anneli Marian Drecker
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by Vernon Dalhart
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by Tirania
Trina
by: Trina(Dee)
Yeah, Look here Trina
Look me and you we been friends for a minutes, but you know how we get down.
Late nights you know how we do.
We go our seperate ways, but lately I been feelin kinda different like me catchin feelings for you.
You know when you callm e daddy, and all that.
When you comb my hair? For real.
(Verse 1 - Dee)
I never knew that I would fall so deep in love with her homie, lover, friend, we were just passionate.
Now you got me feenin for more.
When other niggas used to call you after midnight it never bothered me.
Girl we was only friends right so why does it hurt more and more?
Girl I get excited whenever you call my phone.
I got a special ringer everytime my phone rings it goes,.
" I can't leave you alone,"
You got my feening, feenin, feenin.
So baby i'm pleading for you . bring your body home to me and let me lay you down.
(Chorus)
Girl bring your body home to daddy
Girl i love it when you call my daddy.
Baby you're my sexy lil mama
slip in my bedroom girl, and we can get it on.
Girl bring your body home to daddy
Girl i love it when you call my daddy.
Baby you're my sexy lil mama
slip in my bedroom girl, and we can get it on.
(Verse 2 - Trina)
I'm tired of the fightin, the fussin, and cussin late night discussions
Of who you think i'm f**kin.
You puttin me on guilt trips like I can't see
You storin his name for hers in your caller ID.
Look, i'm a queen the don diva
We should just free in the lime green Selene 2 seater
You & me.
My top down, and Yes my hairs blowin
Flashbacks of you & me got me moanin,
but who you lovin who you want to be huggin?
I seen her in your 600, and you claim its your cousin.
Look, I know we agreed to see other people,
but those feelings got shattered though like my langurae see through.
We both play this game unfaithfully
See me with the next man and now you want to play with me.
Yo, I'm confused, but i still want to proceed
Without you i'm incomplete you make me so week
I love it when you say.
(Chorus)
Girl bring your body home to daddy
Girl i love it when you call my daddy.
Baby you're my sexy lil mama
slip in my bedroom girl, and we can get it on.
Girl bring your body home to daddy
Girl i love it when you call my daddy.
Baby you're my sexy lil mama
slip in my bedroom girl, and we can get it on.
(Verse 3 - Trina)
I remember late nights when we would just kiss.
I remember wearin them girtles & when we would take them trips,
and I remember that we said it would never come to this.
Never let something come between our relationship.
Now how can i leave you to be with someone else?
Without finding out how you truely felt.
All them riding on hoarses and creeping and abortions,
the thoughts of marriage - all white - playin organs.
Started from the ruff sex on the deck of the yatch.
Followed by the Don Perion then the caneri watch.
All them shoes from Italy it was cool,
even the Villa in Sicily, but it wasn't me.
But i should have made it crystal clear that I didn't really care
Whether you was dead broke or you was a millionaire,
From our first date to our anniversary,
My thoughts changed of leaving when I heard you say to me.
(Chorus)
Girl bring your body home to daddy
Girl i love it when you call my daddy.
Baby you're my sexy lil mama
slip in my bedroom girl, and we can get it on.
Girl bring your body home to daddy
Girl i love it when you call my daddy.
Baby you're my sexy lil mama