Drip brew

Drip brewing, filtered coffee, or pour-over is a method which involves pouring water over roasted, ground coffee beans contained in a filter, creating the beverage called coffee. Water seeps through the ground coffee, absorbing its oils and essences, solely under gravity, then passes through the bottom of the filter. The used coffee grounds are retained in the filter with the liquid falling (dripping) into a collecting vessel such as a carafe or pot.

Paper coffee filters were invented in Germany by Melitta Bentz in 1908 and are commonly used for drip brew all over the world. In 1954 the Wigomat, invented by Gottlob Widmann, was patented in Germany being the first electrical drip brewer. Drip brew coffee makers replaced the coffee percolator in the 1970s due to the percolators' tendency to over-extract coffee, thereby making it bitter. One benefit of paper filters is that the used grounds and the filter may be disposed of together, without a need to clean the filter. Permanent filters are now also common, made of thin perforated metal sheets or fine plastic mesh that restrain the grounds but allow the coffee to pass, thus eliminating the need to have to purchase separate filters which sometimes cannot be found in some parts of the world. These add to the maintenance of the machine, but reduce overall cost and produce less waste.

Brew

Brew may refer to:

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Brew (horse)

Brew (foaled 1994 in New Zealand) is a small, plain bay Thoroughbred gelding who won the 2000 Melbourne Cup for trainer Mike Moroney and jockey Kerrin McEvoy. He carried the lightweight of 49.5 kilos and defeated the veteran Yippyio and the stablemate Second Coming. After finishing second to Yippyio in the Moonee Valley Cup, Brew qualified for the Melbourne Cup by winning The Dalgety on Derby Day, three days before the Cup. Brew was a son of the Sir Tristram and the champion New Zealand racemare and Japan Cup winner Horlicks but was gelded before showing his best form. The Melbourne Cup was Brew's last win.

Brew is now at Living Legends, the International Home of Rest for Champion Horses located in Woodlands Historic Park, Greenvale, Victoria, Australia.

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Drip

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DRIP

DRIP may refer to:

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MED1

Mediator of RNA polymerase II transcription subunit 1 also known as DRIP205 or Trap220 is a subunit of the Mediator complex and is a protein that in humans is encoded by the MED1 gene. MED1 functions as a nuclear receptor coactivator.

Function

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The mediator of RNA polymerase II transcription subunit 1 protein is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes [e.g., thyroid hormone receptor-(TR-) associated proteins that interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors]. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.