Donepezil
Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease. Donepezil is used to improve cognition and behavior of people with Alzheimer's, but does not slow the progression of or cure the disease.
Common side effects include loss of appetite, gastrointestinal upset, diarrhea, difficulty sleeping, vomiting, or muscle cramping.
It was developed by Eisai and Pfizer and is sold as a generic by multiple suppliers. Donepezil acts as a centrally acting reversible acetylcholinesterase inhibitor.
Medical uses
Alzheimer's disease
There is no evidence that donepezil or other similar agents alters the course or progression of Alzheimer's disease (AD). A 6 to 12-month controlled studies have shown modest benefits in cognition and/or behavior. The UK National Institute for Clinical Excellence (NICE) recommends donepezil as an option in the management of mild to moderate Alzheimer's disease. The person should, however, be reviewed frequently and if there is no significant benefit it should be stopped. In 2006 the U.S. Food and Drug Administration also approved donepezil for treatment of mild, moderate and severe dementia in Alzheimer's disease.
Podcasts:
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by Toni Basil
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by Toni Basil
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by Toni Basil
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by Toni Basil
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by Toni Basil
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by Toni Basil
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by Toni Basil
Mickey
by: Toni BasilOh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey
Hey, Mickey
You've been around all night and that's a little long
You think you got the right but I think you got it wrong
Oh, can't you say goodnight so you can take me home, Mickey?
'Cause when you say you will, it always means you won't
You're givin' me the chills, baby, please, baby, don't
Every night you still leave me all alone, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Hey, Mickey
Now if you take me by the, who's ever gonna know?
Every time you move, I let a little more show
There's something you can use so don't say no, Mickey
So come on and give it to me anyway you can
Anyway you wanna do it, I'll take it like a man
Oh, please, baby, please, don't leave me in the damn, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind