DMT
DMT may refer to the following:
Chemical substances
Sports
Other uses
2,alpha-DMT
2,alpha-DMT, or 2,α-dimethyltryptamine, is a tryptamine and a lesser-known psychedelic drug. It is the 2,a-dimethyl analog of DMT. 2,α-DMT was first synthesized by Alexander Shulgin. In his book TiHKAL (Tryptamines I Have Known and Loved), Shulgin lists the dosage as 300-500 mg, and the duration as 7-10 hours. 2,α-DMT causes mydriasis and paresthesia. It also produces a calm, drunk-like feeling. Very little data exists about the pharmacological properties, metabolism, and toxicity of 2,α-DMT.
References
External links
DMT1
The divalent metal transporter 1 (DMT1), also known as natural resistance-associated macrophage protein 2 (NRAMP 2), and divalent cation transporter 1 (DCT1), is a protein that in humans is encoded by the SLC11A2 (solute carrier family 11, member 2) gene. DMT1 represents a large family of orthologous metal ion transporter proteins that are highly conserved from bacteria to humans.
As its name suggests, DMT1 binds a variety of divalent metals including cadmium (Cd2+), copper (Cu2+), and zinc (Zn2+,,) however it is best known for its role in transporting ferrous iron (Fe2+); DMT1 expression is regulated by body iron stores to maintain iron homeostasis. DMT1 is also important in the absorption and transport of manganese (Mn2+). In the digestive tract, it is located on the apical membrane of enterocytes, where it carries out H+ coupled transport of divalent metal cations from the intestinal lumen into the cell.
Role in neurodegenerative diseases
Toxic accumulation of divalent metals, especially iron and/or manganese, are frequently discussed aetiological factors in a variety of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. DMT1 may be the major transporter of manganese across the blood brain barrier and expression of this protein in the nasal epithelium provides a route for direct absorption of metals into the brain. DMT1 expression in the brain may increase with age, increasing susceptibility to metal induced pathologies. DMT1 expression is found to be increased in the substantia nigra of Parkinson's patients and in the ventral mesencephalon of animal models intoxicated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) - a neurotoxin widely used experimentally to produce Parkinsonian symptoms.
Girlfriends
Girlfriends is an American situation comedy that premiered on September 11, 2000, on UPN and aired on UPN's successor network, The CW, before being abruptly cancelled in 2008. The final episode aired on February 11, 2008. When Girlfriends returned in fall 2007 for its eighth season, it became the longest-running live-action sitcom on network television that was on air that fall 2007.
It was one of the highest-rated scripted shows on television among African-American adults 18-34, including its spin-off The Game.
Production
The series debuted on UPN on Monday September 11, 2000. After airing for several years on the network at 9/8C on Mondays, The CW moved Girlfriends to Sundays at 8/7C. The ratings plummeted. On October 9, 2006, Girlfriends, along with The CW's other African-American programs, moved back to Mondays. At this point, Girlfriends returned to its original time slot.
While UPN was still airing new episodes of Girlfriends, the network also began airing reruns five days per week. When the show moved to The CW network after UPN merged with The WB network, MyNetwork TV (which was created to take over UPN's former affiliate stations) picked up the rights to air reruns of Girlfriends, although they eventually discontinued this. WE tv, a network with primarily women's programming, later acquired exclusive rights to air the limited-release episodes on Sundays and exercised an option to not allow broadcast television networks re-broadcast rights to these reruns.
Girlfriends (2009 film)
Girlfriends (Hangul: 걸프렌즈; RR: Gyeolpeurenjeu) is a 2009 South Korean romantic comedy film starring Kang Hye-jung, Han Chae-young, Huh E-jae and Bae Soo-bin.
It is based on the 2007 chick lit novel of the same title by Lee Hong, which won the 31st Writer of Today Award.
Plot
29-year-old Song-yi (Kang Hye-jung) starts dating her handsome co-worker Jin-ho (Bae Soo-bin). But when she suspects Jin-ho might be cheating on her, she sets out to meet the "other woman," only to learn that he has not one, but two, other "girlfriends": Jin (Han Chae-young), Jin-ho's first love, is a sexy and successful party planner, while Bo-ra (Huh E-jae) is a fearless, young college student. On one hand, Song-yi wants to keep Jin-ho all to herself, but strangely enough, she grows close to the two other women and their similar taste in men becomes the basis of a great friendship.
Cast
Girlfriends (Flight of the Conchords)
"Girlfriends" is the eighth episode of the HBO comedy series Flight of the Conchords. This episode first aired in the United States on Sunday, August 5, 2007.
Plot synopsis
Jemaine has his eye on a woman that works at the bakery. He wants Bret to go in the shop with him but Bret is reluctant because he doesn't like croissants. Eventually Jemaine convinces him to be his 'wingman'. While speaking to the woman and her colleague, Jemaine tries speaking a bit of French and they launch into a 1960s French style music video singing "Foux Du Fafa".
Later, on a double date at a nightclub, Jemaine is having trouble getting Lisa, the woman he liked at the croissant shop, interested in him. He convinces Bret to swap partners, but has no better luck with Felicia. Meanwhile Bret is uncomfortable with Lisa's aggressive advances.
At a band meeting Jemaine tells Murray about their new 'girlfriends'. At first a concerned Murray tells them that he thinks bands shouldn't have girlfriends, citing Wham! as an example of a successful band that followed that principle. But then he interrogates the guys for the juicy details. He then tells them that he has some good news. He has met A.J. Jones, supposedly the brother of Quincy Jones, who has sold him a high-end stereo system for $50.
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