District X

District X, also known as Mutant Town or the Middle East Side, is a fictional location in Marvel Comics. It is a neighborhood in New York City, first seen during Grant Morrison's run on the series New X-Men in New X-Men #127, which was primarily populated by mutants. The ghetto was established in Alphabet City, Manhattan (also known as Loisaida), a neighborhood in the East Village (located between Avenues A to D, and between Houston and 14th Streets). This would fall within New York's 12th congressional district and the New York City Council's 2nd district. According to the front cover of X-Factor #31, it had a population of 743, but was more populated prior to the Decimation.

District X also refers to a short-lived comic book series, which ran for 14 issues between May 2004 and June 2005, about the neighborhood and its inhabitants. The series was a police procedural, starring Bishop and Ismael Ortega, who investigated crimes committed by and against the ghetto's mutant residents. The series also explored Ortega's complicated personal relationships and gradual descent into drug abuse and adultery. The series was renamed Mutopia X for five issues, between July 2005 and November 2005, as part of the crossover House of M event, prior to its cancellation. The series was written by David Hine.