Anorexia nervosa

Anorexia nervosa, often referred to simply as anorexia, is an eating disorder characterized by a low weight, fear of gaining weight, a strong desire to be thin, and food restriction. Many people with anorexia see themselves as overweight even though they are underweight. If asked they usually deny they have a problem with low weight. Often they weigh themselves frequently, eat only small amounts, and only eat certain foods. Some will exercise excessively, force themselves to vomit, or use laxatives to produce weight loss. Complications may include osteoporosis, infertility and heart damage, among others. Women will often stop having menstrual periods.

The cause is not known. There appear to be some genetic components with identical twins more often affected than non-identical twins. Cultural factors also appear to play a role with societies that value thinness having higher rates of disease. Additionally, it occurs more commonly among those involved in activities that value thinness such as high level athletics, modelling, and dancing. Anorexia often begins following a major life change or stress inducing event. The diagnosis requires a significantly low weight. The severity of disease is based on body mass index (BMI) in adults with mild disease having a BMI of greater than 17, moderate a BMI of 16 to 17, severe a BMI of 15 to 16, and extreme a BMI less than 15. In children a BMI for age percentile of less than the 5th percentile is often used.

Anorexia (symptom)

Anorexia is the decreased sensation of appetite. While the term in non-scientific publications is often used interchangeably with anorexia nervosa, many possible causes exist for a decreased appetite, some of which may be harmless, while others indicate a serious clinical condition or pose a significant risk.

For example, anorexia of infection is part of the acute phase response (APR) to infection. The APR can be triggered by lipopolysaccharides and peptidoglycans from bacterial cell walls, bacterial DNA, double-stranded viral RNA, and viral glycoproteins, which can trigger production of a variety of proinflammatory cytokines. These can have an indirect effect on appetite by a number of means, including peripheral afferents from their sites of production in the body, by enhancing production of leptin from fat stores. Inflammatory cytokines can also signal to the central nervous system more directly by specialized transport mechanisms through the blood–brain barrier, via circumventricular organs (which are outside the barrier), or by triggering production of eicosanoids in the endothelial cells of the brain vasculature. Ultimately the control of appetite by this mechanism is thought to be mediated by the same factors normally controlling appetite, such as neurotransmitters (serotonin, dopamine, histamine, norepinephrine, corticotropin releasing factor, neuropeptide Y, and α-melanocyte-stimulating hormone).

Anorexia (disambiguation)

Anorexia may refer to:

Eating conditions

Relationships

Music

See also

Distance

Distance is a numerical description of how far apart objects are. In physics or everyday usage, distance may refer to a physical length, or an estimation based on other criteria (e.g. "two counties over"). In mathematics, a distance function or metric is a generalization of the concept of physical distance. A metric is a function that behaves according to a specific set of rules, and is a concrete way of describing what it means for elements of some space to be "close to" or "far away from" each other. In most cases, "distance from A to B" is interchangeable with "distance between B and A".

Overview and definitions

Physical distances

A physical distance can be mean several different things:

Distance (Dan Michaelson and The Coastguards album)

Distance is the fourth album by Dan Michaelson aka Dan Michaelson and The Coastguards. Released by London label The state51 Conspiracy in August 2014.

A video, directed by Edward Mantle, was created for the second single, Bones.

Track listing

References

Cosmic distance ladder

The cosmic distance ladder (also known as the extragalactic distance scale) is the succession of methods by which astronomers determine the distances to celestial objects. A real direct distance measurement of an astronomical object is possible only for those objects that are "close enough" (within about a thousand parsecs) to Earth. The techniques for determining distances to more distant objects are all based on various measured correlations between methods that work at close distances and methods that work at larger distances. Several methods rely on a standard candle, which is an astronomical object that has a known luminosity.