Disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC), also known as disseminated intravascular coagulopathy or less commonly as consumptive coagulopathy, is a pathological process characterized by the widespread activation of the clotting cascade that results in the formation of blood clots in the small blood vessels throughout the body. This leads to compromise of tissue blood flow and can ultimately lead to multiple organ damage. In addition, as the coagulation process consumes clotting factors and platelets, normal clotting is disrupted and severe bleeding can occur from various sites.

DIC does not occur by itself but only as a complicating factor from another underlying condition, usually in those with a critical illness. The combination of widespread loss of tissue blood flow and simultaneous bleeding leads to an increased risk of death in addition to that posed by the underlying disease. DIC can be overt and severe in some cases, but milder and insidious in others. The diagnosis of DIC depends on the findings of characteristic laboratory tests and clinical background. Treatment is mainly geared towards the underlying condition.

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Latest News for: disseminated intravascular coagulation

Lucy Letby murder convictions: what did the expert panel find?

AOL 04 Feb 2025
The panel concluded that baby four had died from systemic sepsis, pneumonia and disseminated intravascular coagulation, where blood clots form throughout the circulatory system. The mother should have received antibiotics in pregnancy, the panel said.

The 14 hospital 'failures' which experts claim exonerates serial child killer Lucy Letby | Daily ...

The Daily Mail 04 Feb 2025
'We did not find any murders.' ... I did this' ... The panel found no evidence of air embolism and ruled the child died of systemic sepsis, pneumonia and disseminated intravascular coagulation (blood clotting) ... Advertisement ... He said ... Recap ... NADINE DORRIES ... .

Lucy Letby press conference: nurse ‘did not murder any babies’

The Times/The Sunday Times 04 Feb 2025
What you need to know. The evidence used to convict serial killer Lucy Letby has been challenged today by a panel of medical experts ... 1.30pm ... On baby four he said the cause of death was sepsis, pneumonia and disseminated intravascular coagulation ... Davis.

Medical experts reviewing Lucy Letby case in bid overturn killer's 15 whole-life orders claim they ...

The Daily Mail 04 Feb 2025
'We did not find any murders.' ... And Dr Lee told the packed press conference ... In summary, ladies and gentlemen, we did not find any murders ... LIVE ... Dr Lee said the baby died from 'systemic sepsis, pneumonia and disseminated intravascular coagulation' ... .
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