A disease is a particular abnormal condition, a disorder of a structure or function, that affects part or all of an organism. The causal study of disease is called pathology. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by factors originally from an external source, such as infectious disease, or it may be caused by internal dysfunctions, such as autoimmune diseases. In humans, "disease" is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person afflicted, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structure and function, while in other contexts and for other purposes these may be considered distinguishable categories. Diseases usually affect people not only physically, but also emotionally, as contracting and living with a disease can alter one's perspective on life, and one's personality.
In thermodynamics, entropy (usual symbol S) is a measure of the number of specific realizations or microstates that may realize a thermodynamic system in a defined state specified by macroscopic variables. Entropy is commonly understood as a measure of molecular disorder within a macroscopic system. According to the second law of thermodynamics the entropy of an isolated system never decreases. Such a system spontaneously evolves towards thermodynamic equilibrium, the state with maximum entropy. Systems that are not isolated may decrease in entropy, provided they increase the entropy of their environment by at least that same amount. Since entropy is a state function, the change in the entropy of a system is the same for any process that goes from a given initial state to a given final state, whether the process is reversible or irreversible. However, irreversible processes increase the combined entropy of the system and its environment.
The change in entropy (ΔS) of a system was originally defined for a thermodynamically reversible process as
Disorder (Italian: Il disordine, French: Le Désordre) is a 1962 Italian-French comedy-drama film directed by Franco Brusati. For his performance Georges Wilson won the Golden Gate Award for Best Supporting Actor at the San Francisco International Film Festival.
Shakaya is the first studio album by Australian girl duo Shakaya, released in Australia on 18 October 2002 (see 2002 in music) by Columbia. The album has a mix genre of pop and R&B songs — written by the duo themselves and their manager/producer Reno Nicastro.
The album debuted at number five on the Australian ARIA Charts and stayed in the top fifty for two weeks and in the chart for six weeks. It also made an appearance in the Australasian Album Chart, peaking at number two (just missing the number one spot by Barricades & Brickwalls by Kasey Chambers).
Shakaya produced one top ten and two top twenty hits on the Australian ARIA Singles chart: "Stop Calling Me", "Sublime" and "Cinderella".
Sublime was an American ska punk / reggae rock band from Long Beach, California, formed in 1988. The band's line-up, unchanged until their breakup, consisted of Bradley Nowell (vocals and guitar), Eric Wilson (bass) and Bud Gaugh (drums). Lou Dog, Nowell's dalmatian was the mascot of the band. Michael 'Miguel' Happoldt and Marshall Goodman "Ras MG" contributed to and co-wrote several Sublime songs. Nowell died of a heroin overdose in 1996. In 1997, posthumous songs such as "What I Got", "Santeria", "Wrong Way", "Doin' Time", and "April 29, 1992 (Miami)" were released to U.S. radio.
Sublime released three studio albums, one live album, five compilation albums (one of which also contains never-before released material), three EPs and one box set. Although their first two albums—40oz. to Freedom (1992) and Robbin' the Hood (1994)—were quite popular in the United States, Sublime did not experience major commercial success until 1996 with their self-titled third album, released two months after Nowell's death, which peaked at No. 13 on the Billboard 200, and spawned the single "What I Got", which remains the band's only No. 1 hit single (on the Billboard Alternative Songs chart) in their musical career. As of 2009, the band has sold over 17 million albums worldwide, including about 10 million in the U.S. alone.
Sublime is the eponymous third and final studio album by American ska punk band Sublime. Produced by Paul Leary and David Kahne, the album was released on July 30, 1996 in the United States by MCA Records. Sublime formed in 1988 in Long Beach, California by vocalist/guitarist Bradley Nowell, bassist Eric Wilson, and drummer Bud Gaugh. The trio toured heavily from their inception while developing their sound. Their first studio release — 40 Oz. to Freedom (1992) — featured the single "Date Rape", which attracted heavy airplay in Southern California. MCA signed the band and distributed their second independent album, Robbin' the Hood, in 1994.
By the time it came to record their major label debut, Nowell had been struggling with a heroin addiction. Sublime was recorded over a period of three months in Austin, Texas, in sessions characterized by heavy drug use and raucous partying. The album's musical style contains elements of punk rock, reggae, and ska, as well as dancehall, hip hop, and dub music, with tempos ranging wildly. Nowell's lyrical subject matter relates to relationships, prostitution, riots, and addiction. Nowell had been ejected from the recording near its completion, and was found dead of a heroin overdose in May 1996, two months prior to its release, leading to the band's dissolution.