Glioma

A glioma is a type of tumor that starts in the brain or spine. It is called a glioma because it arises from glial cells. The most common site of gliomas is the brain. Gliomas make up about 30% of all brain and central nervous system tumors and 80% of all malignant brain tumors.

Classification

Gliomas are classified by cell type, by grade, and by location.

By type of cell

Gliomas are named according to the specific type of cell with which they share histological features, but not necessarily from which they originate. The main types of gliomas are:

  • Ependymomas: ependymal cells
  • Astrocytomas: astrocytes (glioblastoma multiforme is a malignant astrocytoma and the most common primary brain tumor among adults).
  • Oligodendrogliomas: oligodendrocytes
  • Brainstem glioma: develop in the brain stem
  • Optic nerve glioma: develop in or around the optic nerve
  • Mixed gliomas, such as oligoastrocytomas, contain cells from different types of glia
  • By grade

    Gliomas are further categorized according to their grade, which is determined by pathologic evaluation of the tumor.

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