Desvenlafaxine
Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.
Medical uses
Desvenlafaxine's primary use in medicine is the treatment of major depressive disorder.
Adverse effects
Adverse effect incidence
Very common (>10% incidence) adverse effects include:
Nausea
Headache
Dizziness
Dry mouth
Hyperhidrosis
Diarrhoea
Insomnia
Constipation
Fatigue
Common (1-10% incidence) adverse effects include:
Tremor
Blurred vision
Mydriasis
Decreased appetite
Sexual dysfunction
Insomnia
Anxiety
Elevated cholesterol and triglycerides
Proteinuria
Vertigo
Feeling jittery
Asthenia
Nervousness
Hot flush
Irritability
Abnormal dreams
Urinary hesitation
Yawning
Rash
Uncommon (0.1-1% incidence) adverse effects include: