In chess, a desperado piece is a piece that seems determined to give itself up, typically either (1) to sell itself as dearly as possible in a situation where both sides have hanging pieces or (2) to bring about stalemate if it is captured, or in some instances, to force a draw by threefold repetition if it is not captured (Hooper & Whyld 1992:106–7). Andrew Soltis describes the former type of desperado as "a tactical resource in which you use your doomed piece to eat as much material as possible before it dies" (Soltis 1975:246).
A simple example illustrating the first definition comes from a 1958 game between future World Champions Tigran Petrosian and Bobby Fischer (see diagram). White had just captured the e5-pawn with his knight on f3. The white knight can be taken, but White's move also opened a discovered attack on the black knight on h5. If Black takes the knight, then 13.Qxh5 leaves him a pawn down. To avoid this, Black sacrificed the h5-knight for material:
Desperado is a hypercoaster located in Primm, Nevada, United States at the Buffalo Bill's Hotel and Casino a part of the Primm Valley Resorts complex.
According to the roller coaster database, Desperado was one of the tallest roller coasters in the world at the time of being built. It features a 60-degree, 225-foot (69 m) drop; a 209-foot (64 m) lift hill; and top speeds around 80 mph. On the 2 minute, 43 second ride, riders will experience almost 4 Gs. A portion of the ride runs through the interior of the casino. The coaster was listed by the Guinness Book of Records as the world's tallest roller coaster in 1996. It is the only Hypercoaster in the state of Nevada. The ride was provided by Arrow Dynamics and fabricated by Intermountain Lift, Inc.
Built by Gary Primm to attract those driving by on adjacent Interstate 15 to his new casino, Buffalo Bill's, opened on May 14, 1994. Desperado was not completed when the casino opened, premiering three months later. At its opening in August, the coaster tied the record for steepest and longest drop (225 feet). However, the top speed of 80 mph was slightly slower than Steel Phantom at Kennywood which had a top speed of 82 mph. When the ride opened, some questioned if the 209' lift height was higher than The Pepsi Max Big One at Blackpool Pleasure Beach in England. The Big One opened in May 1994, with a top speed of 75 mph and an advertised height of 235', but many suspected that number was actually above sea level which was several feet lower than The Big One's base. Ron Toomer of Arrow Dynamics confirmed the Big One's height is 213 feet from the ground with a drop of 205 feet.
Desperado is the second studio album by the American band the Eagles. It was recorded at Island Studios in London, England and released in 1973. The songs on Desperado are based on the themes of the Old West. The band members are featured on the album's cover dressed like an outlaw gang; Desperado remains the only Eagles album where the band members appear on the front cover.
Although the title track is one of the Eagles' signature songs, it was never released as a single. The song "Desperado" was ranked No. 494 on Rolling Stone's 2004 list of "The 500 Greatest Songs of All Time". The album did yield two singles, though: "Tequila Sunrise" and "Outlaw Man". Those two singles reached No. 64 and No. 59 respectively. The album reached No. 41 on the Billboard album chart and was certified Gold by the RIAA on September 23, 1974, and double platinum on March 20, 2001.
Desperado was the last Asylum Records album to be distributed in North America by Atlantic Records (catalog no. SD 5068), prior to Asylum's mid-1973 merger with Elektra Records by Asylum's, Elektra's and Atlantic's parent company, Warner Communications.
STI may refer to:
Imatinib (INN), marketed by Novartis as Gleevec (Canada, South Africa and the USA) or Glivec (Australia, Europe and Latin America), and sometimes referred to by its investigational name STI-571, is a tyrosine-kinase inhibitor used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML).
In order to survive, cells need signaling through proteins (signal cascade) to keep them alive. Some of the proteins in this cascade use a phosphate group as an "on" switch. This phosphate group is added by a tyrosine kinase enzyme. In healthy cells, these tyrosine kinase enzymes are turned on and off as needed. In Ph-positive CML cells, one tyrosine kinase enzyme, BCR-Abl, is stuck on the "on" position, and keeps adding phosphate groups. Imatinib blocks this BCR-Abl enzyme, and stops it from adding phosphate groups. As a result, these cells stop growing, and even die by a process of cell death (apoptosis). Because the BCR-Abl tyrosine kinase enzyme exists only in cancer cells and not in healthy cells, imatinib works as a form of targeted therapy—only cancer cells are killed through the drug's action. In this regard, imatinib was one of the first cancer therapies to show the potential for such targeted action, and is often cited as a paradigm for research in cancer therapeutics.
Subaru Tecnica International (スバルテクニカインターナショナル株式会社, Subaru Tekunika Intānashonaru Kabushiki-gaisha), or STI (prior to 2006, STi), is Fuji Heavy Industries' motorsports division. STI, along with Prodrive of the UK specialized in the preparation of a variety of vehicles for the Subaru World Rally Team which competed in the World Rally Championship (WRC). It was founded in 1988 by Fuji Heavy Industries, the parent company of Subaru, to promote the company's performance-oriented identity.
STI's signature color is "Cherry Blossom Red" (or "Rubine Red" as it is known in Australia.) It is seen as a masculine colour in Japanese culture.
While Subaru offers many models with a trim level labeled "STI" or "Tuned by STI," there have been several special limited edition STI models.
STI was also known for its exceptional quality in producing cars designed for rally racing. Subaru discontinued its participation in the WRC in 2008.