DSCAM
DSCAM and Dscam are both abbreviations for Down Syndrome Cell Adhesion Molecule. The case difference between the two abbreviations is significant as DSCAM refers to the gene that encodes for the Dscam protein.
Down Syndrome (DS), caused by trisomy 21, is the most common birth defect associated with intellectual disability. Recently, the novel gene DSCAM has been identified in the DS critical region. DSCAM is predicted to be a transmembrane protein with a very high structural and sequence homology to the immunoglobulin (Ig) superfamily of cell adhesion molecules. It is expressed in the developing nervous system with the highest level of expression occurring in the fetal brain. When this gene is over-expressed in the developing fetal central nervous system, it leads to Down syndrome. Diverse glycoproteins of cell surfaces and extracellular matrices, operationally termed as 'adhesion molecules' are important in the specification of cell interactions during development as well as maintenance and regeneration of the nervous system.
Podcasts:
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by Skylark
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by Rodgau Monotones
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by Screamers
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by Rawhead Rexx
The Scream
by: Skylark[Princess of the Snow and Captain of the Warriors together:]
Fantasy, is just a word to fall in love.
Agony is what today affects our soul.
[Princess of the Snow:]
There's no White Warrior on our side, there are no chances to survive
We have just opened the Last Gate.
Not a Knight but just an evil disciple.
Not so White but Black as much as Belzebu.
[The Warriors:]
Run because it's coming Belzebu
[Princess of the Snow:]
He made a pact for vanity, searching the glory just for him,
this what is hidden in the Gate. So...
I scream for more, to change this day,
but now my time has come and gone,
and we can't win the game.
I scream for more, to stop this fall,
but now the evil seats so close and we can't free our soul,
so I scream alone.
We have fought in a battle with nothing to win,
and White Warrior, our Symbol, was only a dream.
Now the path that we are walking might lead to nowhere,
Only time can tell.
[Princess of the Snow and Captain of the Warriors together:]
Fantasy, is just a word to fall in love.
Agony is what today affects our soul.
[Princess of the Snow:]
Now we will sing so loud this song, but we don't know what we look for,