Adhesins are cell-surface components or appendages of bacteria that facilitate adhesion or adherence to other cells or to surfaces. Adhesins are a type of virulence factor.
Adherence is an essential step in bacterial pathogenesis or infection, required for colonizing a new host.
Bacteria are typically found attached to and living in close association with surfaces. During the bacterial lifespan, a bacterium is subjected to frequent shear-forces. In the crudest sense, bacterial adhesins serve as anchors allowing bacteria to overcome these environmental shear forces, thus remaining in their desired environment. However, bacterial adhesins do not serve as a sort of universal bacterial Velcro. Rather, they act as specific surface recognition molecules, allowing the targeting of a particular bacterium to a particular surface such as root tissue in plants, lacrimal duct tissues in mammals, or even tooth enamel.
Most fimbria of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. To effectively achieve adherence to host surfaces, many bacteria produce multiple adherence factors called adhesins.
The Diccionario de la lengua española, also known as the Diccionario de la Real Academia Española (DRAE), is the authoritative dictionary of the Spanish language. It is produced, edited, and published by the Real Academia Española (RAE – Royal Spanish Academy). The first edition was published in 1780. The twenty-third edition was published in 2014.
When the RAE was founded in 1713, one of its primary objectives was compiling a Castilian Spanish dictionary. Its first endeavor was the six-volume Diccionario de Autoridades (Dictionary of Authorities) from 1726 to 1739. Based on that work, an abridged version was published in 1780, the full title of which was the Diccionario de la lengua castellana compuesto por la Real Academia Española, reducido á un tomo para su más fácil uso (Dictionary of the Castilian language composed by the Royal Spanish Academy, reduced to one volume for easier use). According to its prologue, the dictionary was published for general public access to a dictionary during the long time between the publishing of the first and second editions of the exhaustive Authorities Dictionary, thus offering a cheaper reference book; by the time the second edition was published, it had become the principal dictionary, superseding its ancestor; the last edition of the Diccionario de Autoridades was published in 1793.
I love You, Lord, I worship You
I love You, Lord, always
So thankful Lord, You saved my life
You saved my life today
Let me be a shining light for You
Let me be a joy to You always
Let me be a shining light for You
Let me be a joy to You always, yeah, yeah
No Superman, I'm no hero
I'm just a man in Your eyes
But through Your son I've overcome
The Father of all lies
Let me be a shining light for You
Let me be a joy to You always
Let me be a shining light for You
Let me be a joy to You always, yeah, yeah, yeah
Hallelujah, Hallelujah
Hallelujah, Hallelujah
No Superman, I'm no hero
I'm just a man in Your eyes
But through Your son I've overcome
The Father of all lies
Let me be a shining light for You
Let me be a shining light for You
Let me be a joy to You always
Let me be a shining light for You
Let me be a joy to You always
Let me be a shining light for You
Let me be a joy to You always
Let me be a shining light for You
Let me be a joy to You always
Let me be a joy to You always
Let me be a joy to You always
I wanna be a joy to You always
Let me be a joy to You always
Hallelujah, Hallelujah