Cytarabine
Cytarabine or cytosine arabinoside (Cytosar-U or Depocyt) is a chemotherapy agent used mainly in the treatment of cancers of white blood cells such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma. It is also known as ara-C (arabinofuranosyl cytidine). It kills cancer cells by interfering with DNA synthesis.
It is called cytosine arabinoside because it combines a cytosine base with an arabinose sugar. Cytosine normally combines with a different sugar, deoxyribose, to form deoxycytidine, a component of DNA. Certain sponges, where it was originally found, use arabinoside sugars to form a different compound (not part of DNA). Cytosine arabinoside is similar enough to human cytosine deoxyribose (deoxycytidine) to be incorporated into human DNA, but different enough that it kills the cell. This mechanism is used to kill cancer cells. Cytarabine is the first of a series of cancer drugs that altered the sugar component of nucleosides. Other cancer drugs modify the base.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
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Hitohira No Hanabira
by: Stereo PonyHitohira no hanabira ga yurete iru boku no tonari de ima
Machigatta koi datta sonna koto omoitaku wa nai
Tel no mukou kurai kao shiteru
Kiridasu kotoba ni obietenda
Ittai itsu kara bokura konna kimochi ni
Kizukanai furi tsuzukete tanda
Deatta hi no you na ano suki tooru kaze no naka de
Yarinaoseru no nara mou ichido dakishimetai
Hitohira no hanabira ga yurete iru boku no tonari de ima
Machigatta koi datta sonna koto omoitaku wa nai
Suki datta hazu datta itsu datte koe ga kikitaku naru hodo
Sore nanoni te ga todoku saki no kimi ga mienaku narisouda
Heiki datte sugu gaman shiteta nowa
Kitto bokutachi no warui toko de
Itsumo issho ni itaitte omotteta noni
Surechigai wa genjitsu wo kaeta
Deatta hi no you na ano yawaraka na egao datte
Sugu ni tori modoseru ki ga shiteta dakishimetai
Hitohira no hanabira ga yurete iru boku no tonari de ima
Machigatta koi datta sonna koto omoitaku wa nai
Damatta mama no kimi no te no hira
Tadori tsuita namida ga hajiketa
Konna bokutachi no jikan wo maki modoshite
Hitohira no hanabira ga mai ochita boku no tonari de ima
Machigatta koi datta nante wasurerareru hazu wa nainda
Suki datta suki datta ima datte sugari tsukitaku naru hodo