Cvid
Cvid stands for
and is also used to refer to the video codec Compact Video or
Common variable immunodeficiency
Common Variable Immunodeficiency (CVID) is an immune disorder characterized by recurrent infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM and IgA. It is thought to infect between 1 in 25,000 to 1 in 50,000 people worldwide. CVID is a rare primary immunodeficiency, and can take many forms due to the diverse ways in which antibody production can be impaired. Generally, CVID symptoms include high susceptibility to foreign invaders, chronic lung disease, and inflammation and infection of the gastrointestinal tract. However, symptoms vary greatly, making the disease not only phenotypically heterogeneous, but also hard to diagnose, taking on average 6-7 years after onset.
CVID is a lifelong disease, but its origin is poorly understood. Current research points to particular genetic markers, like deletions in the CD19, CD20, CD21, and CD80 genes, as likely sources of the disease. Additionally, the disease is defined by T cell defects, namely reduced proliferative capacity. CVID is formally diagnosed by levels of IgG and IgA less than two standard deviations from the mean for age and no other cause for hypogammaglobulinemia, an abnormally low level of immunoglobulins in the blood.
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Latest News for: cvid
Pharming Group N.V., - Pharming Group announces first patient dosed in Phase II clinical trial of leniolisib for common variable immunodeficiency (CVID) with immune dysregulation (Pharming Group NV)
Pharming Group announces first patient dosed in Phase II clinical trial of leniolisib for common variable immunodeficiency (CVID) with immune dysregulation (Pharming Group NV)
Pharming Group announces first patient dosed in Phase II clinical trial of leniolisib for common variable immunodeficiency (CVID) with immune dysregulation (Form 6-K) (Pharming Group NV)
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