Corin Curschellas (Romansh pronunciation: [ˌkɔrin kur'ʃe:lɐs]; born 2 July 1956) is a Swiss singer-songwriter, vocalist (jazz, folk music, world music, chanson), free improvisation, actress (theatre, film, musical), voice actress in (radio drama and audio books) as well as voice instructress.
Curschellas was born in 1956 in Chur (Graubünden, Switzerland where she grew up. She attended the local state school in Chur, Kantonsschule Chur, and completed her studies in 1977 with a Primary Teacher’s Certificate.
From 1977 to 1983 she studied theatre and theatre pedagogy at the Zurich University of the Arts a well as three semesters of Music Sciences at the University of Zurich.
From 1983 until 1989 Curschellas lived in Berlin, followed by two years in Basel. A grant she received enabled her to move to Paris in 1991, where she ended up living until 2000, with a two-year break she spent in New York from 1995 to 1997. Between 2000 and 2005 she alternated between Paris and Zürich.
Corin is a unisex given name, and may refer to
This is a list of characters in the series of fantasy novels by C. S. Lewis called The Chronicles of Narnia. See also a list of portrayals.
Corin, also called atrial natriuretic peptide-converting enzyme, is a protein that in humans is encoded by the CORIN gene.
The CORIN gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains.
Human corin, a polypeptide of 1042 amino acids, consists of an N-terminal cytoplasmic domain, a transmembrane domain and an extracellular region with two frizzled-like domains, eight LDL receptor-like domains, a scavenger receptor-like domain and a C-terminal trypsin-like serine protease domain. Corin is synthesized as a zymogen that is activated by PCSK6.
Corin exhibits a trypsin-like catalytic activity favoring basic residues at the P1 position.
Human corin contains 19 N-glycosylation sites.N-glycans promote corin expression on the cell surface and protect corin from metalloproteinase-mediated shedding.
Corin converts the atrial natriuretic peptide (ANP) precursor, pro-ANP, to mature ANP, a cardiac hormone that regulates salt-water balance and blood pressure. In mice, corin deficiency prevents pro-ANP processing and causes salt-sensitive hypertension.