Corin

Corin is a unisex given name, and may refer to

First name

  • Corin Hewitt (born 1971), American sculptor and photographer
  • Corin Forshaw (born 1980), British reality TV star
  • Corin Mellor (born 1966), British designer
  • Corin Nemec (born 1971), American actor
  • Corin Redgrave (1939-2010), British actor and political activist
  • Corin Thunderfist, fictional character and twin of Cor in The Chronicles of Narnia
  • Corin Tucker (born 1972), American singer and guitarist
  • Surname

  • Joshua Corin, American writer
  • Lucy Corin, American writer
  • William Corin (1867-1929), Australian electrical engineer
  • Related Names

  • Corina
  • Corine
  • Corineus
  • Korin
  • List of The Chronicles of Narnia characters

    This is a list of characters in the series of fantasy novels by C. S. Lewis called The Chronicles of Narnia. See also a list of portrayals.

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  • Adaptations
  • External links
  • A

  • Ahoshta: a 60-year-old Tarkaan of Calormen who later becomes the Grand Vizier, chief adviser to the Tisroc (king). Aravis' stepmother arranged for her to marry him, but Aravis hated him because of his age, appearance, character, and base birth. (HHB)
  • Alambil: "Lady of Peace", a planet (moving star) in the heavens above Narnia (PC)
  • Alimash: Calormene nobleman, cousin of Aravis (HHB)
  • Anradin Tarkaan: Calormene nobleman, former owner of Bree, who wants to buy Shasta; killed by King Lune (HHB)
  • Aravis Tarkheena: the daughter of a Calormene nobleman; she flees when her stepmother attempts to marry her to Ahoshta. She escapes from Calormen and becomes Queen of Archenland. (HHB)
  • Ardeeb Tisroc: Great-great-great-great-grandfather of Aravis. (HHB)
  • CORIN

    Corin, also called atrial natriuretic peptide-converting enzyme, is a protein that in humans is encoded by the CORIN gene.

    Protein

    The CORIN gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains.

    Human corin, a polypeptide of 1042 amino acids, consists of an N-terminal cytoplasmic domain, a transmembrane domain and an extracellular region with two frizzled-like domains, eight LDL receptor-like domains, a scavenger receptor-like domain and a C-terminal trypsin-like serine protease domain. Corin is synthesized as a zymogen that is activated by PCSK6.

    Corin exhibits a trypsin-like catalytic activity favoring basic residues at the P1 position.

    Human corin contains 19 N-glycosylation sites.N-glycans promote corin expression on the cell surface and protect corin from metalloproteinase-mediated shedding.

    Function

    Corin converts the atrial natriuretic peptide (ANP) precursor, pro-ANP, to mature ANP, a cardiac hormone that regulates salt-water balance and blood pressure. In mice, corin deficiency prevents pro-ANP processing and causes salt-sensitive hypertension.

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