Proposed top-level domain

The Domain Name System of the Internet consists of a set of top-level domains which constitute the root domain of the hierarchical name space and database. In the growth of the Internet, it became desirable to expand the set of initially six generic top-level domains in 1984. As a result new top-level domain names have been proposed for implementation by ICANN. Such proposals included a variety of models ranging from adoption of policies for unrestricted gTLDs that could be registered by anyone for any purpose, to chartered gTLDs for specialized uses by specialized organizations. In October 2000, ICANN published a list of proposals for top-level domain strings it had received.

Geographic proposals

MED28

Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex.

Function

Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the head module, and components of this submodule act together in a gene-regulatory programme to suppress smooth muscle cell differentiation. Thus, mammalian Mediator subunit Med28 functions as a repressor of smooth muscle-cell differentiation, which could have implications for disorders associated with abnormalities in smooth muscle cell growth and differentiation, including atherosclerosis, asthma, hypertension, and smooth muscle tumours.

Interactions

MED28 has been shown to interact with Merlin,Grb2 and MED26.

See also

References

This article incorporates text from the public domain Pfam and InterPro IPR021640

Further reading

MED6

Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.

Protein family

This family of proteins represent the transcriptional mediator protein subunit 6 that is required for activation of many RNA polymerase II promoters and which are conserved from yeast to humans.

Interactions

MED6 has been shown to interact with:

References

Further reading

External links

This article incorporates text from the public domain Pfam and InterPro IPR007018

Classic (Rah Digga album)

Classic is the second album by American hip hop recording artist Rah Digga. It is her first released since her 2000 debut album Dirty Harriet.

A buzz single entitled "Warning Shots" was released for promotion while "This Ain't No Lil' Kid Rap" was released as the sole single. The album was released through Raw Koncept on September 14, 2010.

Track listing

All songs are produced by Nottz

External links

Rah Digga Talks Comeback LP, Working With Nottz at XXL (magazine)

References

Classic (Adrian Gurvitz song)

"Classic" is a soft rock song by British singer-songwriter Adrian Gurvitz from his 1982 solo album, Classic. It was released as a single in early 1982 and was a big hit in his native UK, reaching the Top 10 and peaking at #8 on the UK Singles Chart.

References

Classic (disambiguation)

A classic is something that is a perfect example of a particular style, something of lasting worth or with a timeless quality.

Classic may also refer to: