Cell cycle checkpoint

Cell cycle checkpoints are control mechanisms in eukaryotic cells which ensure proper division of the cell. Each checkpoint serves as a potential point along the cell cycle, during which the conditions of the cell are assessed, with progression through the various phases of the cell cycle occurring when favorable conditions are met. Currently, there are three known checkpoints: the G1 checkpoint, also known as the restriction or start checkpoint; the G2/M checkpoint; and the metaphase checkpoint, also known as the spindle checkpoint.

Background

All living organisms are products of repeated rounds of cell growth and division. During this process, known as the cell cycle, a cell duplicates its contents and then divides in two. The purpose of the cell cycle is to accurately duplicate each organisms’ DNA and then divide the cell and its contents evenly between the two resulting cells. In eukaryotes, the cell cycle consists of four main stages: G1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G2, during which the growth of cell continues and the cell synthesizes various proteins in preparation for division; and the M (mitosis) phase, during which the duplicated chromosomes (known as the sister chromatids) separate into two daughter nuclei, and the cell divides into two daughter cells, each with a full copy of DNA. Compared to the eukaryotic cell cycle, the prokaryotic cell cycle (known as binary fission) is relatively simple and quick: the chromosome replicates from the origin of replication, a new membrane is assembled, and the cell wall form a septum which divides the cell into two.

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Checkpoint

by Joey Gaskin
Checkpoint

by U.S. Bombs

Checkpoint

by: Joey Gaskin

Red lights won't stop this tonight
You're speeding into traffic
Check your hazard lights
Babe, look over your shoulder
I am pulling you over
I'm checking for ID
License and registration please
I'm checking over your taillights
What’s that, in your backseat?
I'mma need you to pop your trunk
I think you're smuggling
You might just get a ticket
If you get disorderly
Or maybe I might just write you a warning
You didn’t see me coming
Nor the roadblock
You know just what I'm wanting
And now you've gotta to stop
It’s too late to turn around
To take another way home
You’re still in my jurisdiction
And babe now you're in my zone
Tell me where you’re headed
What if I said forget it?
You can’t come through my checkpoint
Without knowing where you're going
I'm not gonna let you go
I don't wanna let you go
I need you to take a ride back with me
From the checkpoint
Baby, you're under my surveillance
Your tags are expired
Do you know their outdated?
If I choose to let you slide
Next time, I'll write you a fine
Why am I going easy on you?
I'm not that type
I'll give you a break
Don’t think this ends my investigation
Cause I show you have a history
Of parking violations
So move along, don't sit still
Why are you hesitating?
Hey lady, cross the line
Don't keep me waiting
You didn’t see me coming
Nor the roadblock
You know just what I'm wanting
And now you've gotta to stop
It’s too late to turn around
To take another way home
You’re still in my jurisdiction
And babe now you're in my zone
Tell me where you’re headed
What if I said forget it?
You can’t come through my checkpoint
Without knowing where you're going
I'm not gonna let you go
I don't wanna let you go
I need you to take a ride back with me
From the checkpoint
Mam,
Please step out the car
You are
Guilty as charged
I was gonna let you go
You’re not gonna let me go
I was gonna let you go
You’re not gonna let me go
I didn’t see this coming
Nor the roadblock
You knew that you were wanted
That's why you never stopped
So what made you turn around
To take another way home?
I think you knew my jurisdiction
Cause now you're in my zone
Tell me where you’re headed
What if I said forget it?
You can’t come through my checkpoint
Without knowing where you're going
I'm not gonna let you go
I don't wanna let you go
I need you to take a ride back with me

Latest News for: checkpoint

Edit

UN records highest number of Israeli checkpoints in 2 decades across occupied Palestinian territory

Middle East Monitor 22 Mar 2025

The UN on Friday reported that it has documented nearly 850 Israeli checkpoints, gates, and other physical obstacles across the occupied Palestinian territory, ...

Edit

Travellers advised to postpone non-essential trips to Johor amid heavy traffic at land checkpoints

Straits Times 21 Mar 2025

ICA said cars and motorcycles had to wait more than two hours to clear immigration ....

Edit

Shreveport Police Department to Conduct Seatbelt Checkpoint (City of Shreveport, LA)

Public Technologies 21 Mar 2025

Shreveport Police Department to Conduct Seatbelt Checkpoint.

Edit

Punjab police foils terrorist attack on Taunsa Checkpoint, earns praise from Interior Minister

Urdu Point 21 Mar 2025

<p>ISLAMABAD, (UrduPoint / Pakistan Point News - 21st Mar, 2025) Punjab Police successfully thwarted an attack by Khariji terrorists on a police checkpoint in Taunsa, earning high praise from ...

Edit

Los Angeles Police Department to Conduct DUI Checkpoints and DUI Saturation Patrol NA25021jl (LAPD - Los Angeles Police Department)

Public Technologies 21 Mar 2025

DUI Checkpoint from 6.00 p.m ... DUI Checkpoint from 6.00 p.m ... DUI Checkpoint from 6.00 p.m ... at Topanga Canyon Boulevard and Marylee Street DUI Checkpoint from 6.00 p.m ... DUI Checkpoint from 6.00 p.m ... DUI Checkpoint from 6.00 p.m.

Edit

TSA intercepts gun at West Virginia International Yeager Airport checkpoint (TSA - Transportation Security Administration)

Public Technologies 21 Mar 2025

A woman was stopped with this loaded gun at the TSA checkpoint at CRW Airport on March ... TSA officials notified the police, who confiscated the weapon and removed the woman from the checkpoint for questioning.

Edit

KP Police foil terrorist attack on Bannu checkpoint, praised for bravery

Urdu Point 20 Mar 2025

... Kinger Pul police checkpoint in Bannu.</p><p>According to Naqvi, the KP police confronted the Khawarij terrorists with remarkable courage, successfully repelling the assault.

Edit

Kyrgyzstan Mulls Over Opening Of Intymak Checkpoint On Border With Uzbekistan

MENA FN 20 Mar 2025

(MENAFN - Trend News Agency) BISHKEK, Kyrgyzstan, March 20. The Chairman of the State Customs Service, Almaz Saliev, and the Presidential Representative in the Osh region, Elchibek Dzhantaev, ... .

Edit

Monterey Park Police Department Holding DUI Checkpoint March 28 (City of Monterey Park, CA)

Public Technologies 19 Mar 2025

) On Friday, March 28, 2025, Monterey Park Police Department will conduct a driving under the influence (DUI) checkpoint from 6 p.m ... DUI checkpoint locations are ...

Edit

Roadside emission survey mistaken for immigration checkpoint

The Signal 19 Mar 2025

He said that many concerned individuals have been approaching the survey area to ask what he was doing and why they were pulling cars over ... Immigration and Customs Enforcement, ICE, or any other government enforcement checkpoint.” ... .

Edit

2 armed men killed in shootout at Maguindanao checkpoint

Manila Standard 19 Mar 2025

Two male individuals were ...

Edit

Fear of flying? Dress rehearsal with full TSA checkpoint, flight experience (TSA - Transportation Security Administration)

Public Technologies 19 Mar 2025

A dress rehearsal at California's San José Mineta International Airport (SJC) put many of those fears to rest. [...] ... Attachments Original document Permalink.

Edit

Sobriety and Safety Checkpoints at Mammoth Cave (NPS - National Park Service)

Public Technologies 19 Mar 2025

). The text version of this document is not available ... Disclaimer ... (noodl. 123125677) .

Edit

Indaptus Therapeutics Initiates Phase 1 Combination Study of Decoy20 with PD-1 Checkpoint Inhibitor Tislelizumab

Nasdaq Globe Newswire 18 Mar 2025

New trial arm to evaluate safety, dosing and preliminary anti-tumor activity in advanced solid tumors. New trial arm to evaluate safety, dosing and preliminary anti-tumor activity in advanced solid tumors ... .

Edit

Traffic checkpoint leads to felony drug arrest in Iredell County

Lincoln Times-News 18 Mar 2025

Sheriff Darren Campbell stated. On March 15, 2025, deputies conducted a Motor Vehicle Violation Checkpoint at the intersection of Snow Creek Road and N. Chipley Ford Road ... .

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Checkpoint

Latest News for: checkpoint

UN records highest number of Israeli checkpoints in 2 decades across occupied Palestinian territory

Travellers advised to postpone non-essential trips to Johor amid heavy traffic at land checkpoints

Shreveport Police Department to Conduct Seatbelt Checkpoint (City of Shreveport, LA)

Punjab police foils terrorist attack on Taunsa Checkpoint, earns praise from Interior Minister

Los Angeles Police Department to Conduct DUI Checkpoints and DUI Saturation Patrol NA25021jl (LAPD - Los Angeles Police Department)

TSA intercepts gun at West Virginia International Yeager Airport checkpoint (TSA - Transportation Security Administration)

KP Police foil terrorist attack on Bannu checkpoint, praised for bravery

Kyrgyzstan Mulls Over Opening Of Intymak Checkpoint On Border With Uzbekistan

Monterey Park Police Department Holding DUI Checkpoint March 28 (City of Monterey Park, CA)

Roadside emission survey mistaken for immigration checkpoint

2 armed men killed in shootout at Maguindanao checkpoint

Fear of flying? Dress rehearsal with full TSA checkpoint, flight experience (TSA - Transportation Security Administration)

Sobriety and Safety Checkpoints at Mammoth Cave (NPS - National Park Service)

Indaptus Therapeutics Initiates Phase 1 Combination Study of Decoy20 with PD-1 Checkpoint Inhibitor Tislelizumab

Traffic checkpoint leads to felony drug arrest in Iredell County

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