Caroverine (Spasmium, Spadon, Tinnex) is a drug used as a spasmolytic and otoneuroprotective (inner ear protective) agent in some countries. It acts as an N-type calcium channel blocker, competitive AMPA receptor antagonist, and non-competitive NMDA receptor antagonist. It also has potent antioxidant effects.
Caroverine has been demonstrated to have a high rate of efficacy in the treatment of cochlear-synaptic tinnitus.