"Say" is a song by John Mayer written for the Rob Reiner film The Bucket List in 2007. It was released as a single on November 20 and is the first commercial single in Mayer's career that was not originally released on one of his albums but added to the special edition re-release of his album, Continuum. In the U.S., it has become the artist's highest charting single to date, reaching number twelve on the Billboard Hot 100 in May, 2008. The song earned Mayer another Grammy Award for Best Male Pop Vocal Performance, his fourth win on the category.
The music video for "Say" was directed by music video director Vem. The song is also referred to as "Say (What You Need to Say)" as this is the main line from the chorus of the song. The song was also the first "assignment" song that Mayer had ever written. He felt a little soul-less in the initial composition, writing just a terribly simple song. He notes that when writing the song "I don't know how much harder it gets than to see a beautiful, bittersweet movie and then have to write a song that matches the tone." Mayer posted the song on his official blog on November 16.
Thomas Say (June 27, 1787—October 10, 1834) was an American entomologist and conchologist. His definitive studies of insects and shells, numerous contributions to scientific journals, and scientific expeditions to Florida, Georgia, the Rocky Mountains, Mexico, and elsewhere made him an internationally-known naturalist. Say has been called the father of American descriptive entomology and American conchology. He served as librarian for the Academy of Natural Sciences of Philadelphia, curator at the American Philosophical Society, and professor of natural history at the University of Pennsylvania.
Born in Philadelphia into a prominent Quaker family, Thomas Say was the great-grandson of John Bartram, and the great-nephew of William Bartram. His father, Dr. Benjamin Say, was brother-in-law to another Bartram son, Moses Bartram. The Say family had a house, "The Cliffs" at Gray's Ferry, adjoining the Bartram family farms in Kingessing township, Philadelphia County. As a boy, Say often visited the family garden, Bartram's Garden, where he frequently took butterfly and beetle specimens to his great-uncle William.
"Say" is a selfwritten song by American pop singer Ryan Cabrera, produced by Daniel James, Leah Haywood for Cabrera's third studio album The Moon Under Water (2008). The track was released as the first single from the album in the first quarter of 2008. This song has won Star Shine magazine's independent song of the year.
Its accompanying music video features Cabrera performing the track and walking in the city. The video features a cameo appearance from Rob Dyrdek.
"Say" received positive responses from some critics, but the single flopped. Chuck Taylor of Billboard magazine described it as "the catchiest, coolest, most immediate release of the year."Allmusic's Stephen Thomas Erlewine referred to the song as a "near-incandescent pop tune almost worthy of Gregg Alexander."
In the United States, the song failed to chart on any of the Billboard charts.
Sigma in cosmology was a property of galaxies used when trying to work out the mystery of galaxies and their supermassive black holes.
In the late 1990s the NUKER experts had made observations with a spectroscope of two galaxies, one of an active galaxy with an active galactic nucleus called NGC10-68 and a dormant galaxy next door to us named Andromeda.
The observations are shown. The light from the centre in Andromeda galaxy was distorted proving the existence of super-massive black holes.
Other observations proved most galaxies had a similar centre whether it be active or dormant.
They then realised that the black holes must have something to do with a galaxy's formation, so they turned to something they thought was useless: the speed of the stars around the edge of the galaxy. This was Sigma, the speed of the stars at the edge of the galaxy supposedly unaffected by the mass of the black hole at the centre.
The NUKER team calculated the sigma of several stars in different galaxies and the mass of the black hole at the (nucleus) centre. They expected no correlation what so ever. But when plotting their results on a Scatter diagram and drawing a line of best fit they ended up with a positive correlation. It appeared that the heavier the black hole at the centre was the faster the stars within the galaxy travelled.
Sigma is an English drum and bass duo consisting of Cameron Edwards and Joe Lenzie. They met at Leeds University at drum and bass nights. Their 2010 collaboration with DJ Fresh, "Lassitude", peaked at number 98 on the UK Singles Chart. Their single "Nobody to Love" topped the UK Singles Chart, becoming their first UK number one. Follow-up single "Changing", featuring Paloma Faith, also got to number one.
Lenzie and Edwards met in 2006 at Leeds University; Cameron was working in local record store Tribe Records and with Echo Location's Obi running local night Event Horizon, while Lenzie was DJing hip-hop and warming up Event Horizon for such acts as Rahzel and Grandmaster Flash. Once they had finished in Leeds, they relocated to London and became a three-piece with Edwards' school friend Ben Mauerhoff, being signed under DJ Fresh's Breakbeat Kaos. After a while, long distances took their toll – Edwards and Mauerhoff were based in Surrey, whereas Lenzie was based in Harpenden, Hertfordshire and they couldn't get three people into the Harpenden studio – and Mauerhoff left. In December 2008 they formed their own record label, Life Recordings (so called because, according to Lenzie, the industry demanded that it be their life). Its inaugural release was a VIP mix of their early Bingo Beats single "El Presidente".
In bone physiology, the bone remodeling period describes the temporal duration (i.e. lifespan) of the basic multicellular unit (BMU) that is responsible for bone turnover. Historically, this was referred to as the sigma (σ) or sigma period, but the terminology is now outdated.
Although bone may appear superficially as a static tissue, it is actually very dynamic, undergoing constant remodeling throughout the life of the vertebrate organism. This occurs with the synchronized action of osteoclasts and osteoblasts, cells that resorb and deposit bone, respectively.
The remodeling period consists of the combined duration of the resorption, the osteoclastic reversal (the phase marked by shifting of resorption processes into formative processes) and the formation periods of bone growth and development. This period refers to the average total duration of a single cycle of bone remodeling at any point on a bone surface.
For the remodeling to occur, appropriate cell signaling occurs to trigger osteoclasts to resorb the surface of the bone, followed by deposition of bone by osteoblasts. Together, the cells in any given particular region of the bone surface that are responsible for bone remodeling are known as the basic multicellular unit (BMU), and it is the average lifespan of the BMU that is referred to as the remodeling period. The size of a BMU is roughly 200μm in diameter, defined by the 100μm diffusion capability in bone.