Sumo (band)

Sumo was a 1980s Argentine alternative rock band, merging post-punk with reggae. Headed by Italian-born Luca Prodan, it remained underground for most of its short activity, but was extremely influential in shaping contemporary Argentine rock. Sumo introduced British post-punk to the Argentine scene, with many lyrics in English. And provided a visceral counterpoint to the progressive and nueva canción influences then dominant in Rock en Español.

History

After living in London and Manchester, hanging out with the members of Joy Division, Italian-born Luca Prodan accepted an invitation to visit a farm in the Traslasierra zone of Córdoba province to kick his heroin habit and relax (he was devastated by the death of Ian Curtis). Arriving in 1981, he started composing and recording songs in a homemade studio. After some time, tired of the quiet life in the countryside, he took off to Buenos Aires (specifically to Hurlingham), looking forward to join its underground music scene.

Argentina was under a repressive military dictatorship, and many music and performing-arts acts kept a low profile to avoid problems with police (Cafe Einstein in the Balvanera district was a favorite venue for such acts, as were some pubs in Olivos). Luca soon found musicians willing to join his reggae-rock vision.

SUMO4

Small ubiquitin-related modifier 4 is a protein that in humans is encoded by the SUMO4 gene.

Function

This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.

Interactions

SUMO4 has been shown to interact with IκBα.

References

Further reading

SUMO3

Small ubiquitin-related modifier 3 is a protein that in humans is encoded by the SUMO3 gene.

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002).[supplied by OMIM]

Interactions

SUMO3 has been shown to interact with ARNTL and Thymine-DNA glycosylase.

References

Further reading

Mark

Mark may refer to:

Christianity

Currency

Mark (dinghy)

The Mark is a single-hander class of small sailing dinghy. The design probably first appeared in the 1960s, at about the same time as the Laser, but never took off as a popular racing class. The Mark is 12 feet (3.7 m) in length, with forward and side buoyancy compartments. A 19 feet (5.8 m) free standing rotating mast stepped far forward in the front buoyancy compartment supports a mainsail.

Gospel of Mark

The Gospel According to Mark (Greek: τὸ κατὰ Μᾶρκον εὐαγγέλιον, to kata Markon euangelion), the second book of the New Testament, is one of the four canonical gospels and the three synoptic gospels. It was traditionally thought to be an epitome (summary) of Matthew, which accounts for its place as the second gospel in the Bible, but most scholars now regard it as the earliest of the gospels. Most modern scholars reject the tradition which ascribes it to Mark the Evangelist, the companion of Peter, and regard it as the work of an unknown author working with various sources including collections of miracle stories, controversy stories, parables, and a passion narrative.

Mark tells of the ministry of Jesus from his baptism by John the Baptist to his death and burial and the discovery of the empty tomb – there is no genealogy or birth narrative, nor, in the original ending at chapter 16, any post-resurrection appearances. It portrays Jesus as a heroic man of action, an exorcist, healer and miracle worker. Jesus is also the Son of God, but he keeps his identity secret, concealing it in parables so that even the disciples fail to understand. All this is in keeping with prophecy, which foretold the fate of the messiah as Suffering Servant. The gospel ends, in its original version, with the discovery of the empty tomb, a promise to meet again in Galilee, and an unheeded instruction to spread the good news of the resurrection.