CTTNBP2
Cortactin-binding protein 2 is a protein that in humans is encoded by the CTTNBP2 gene.
Function
This gene encodes a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton.
Interactions
CTTNBP2 has been shown to interact with:
MOBKL3,
PPP2CA,
RP6-213H19.1,
STRN3, and
STRN.
Model organisms
Model organisms have been used in the study of CTTNBP2 function. A conditional knockout mouse line called Cttnbp2tm1b(KOMP)Wtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping
References
Further reading