Camphorsulfonic acid

Camphorsulfonic acid, sometimes abbreviated CSA or 10-CSA is an organosulfur compound. Like typical sulfonic acids, it is a relatively strong acid that is a colorless solid at room temperature and is soluble in water and a wide variety of organic substances.

This compound is commercially available. It can be prepared by sulfonation of camphor with sulfuric acid and acetic anhydride:

In organic synthesis, CSA and its derivatives can be used as resolving agents for chiral amines and other cations. For example, 3-bromocamphor-8-sulfonic acid was used in the synthesis of enantiopure devazepide.

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Ceragenin

Ceragenins, or cationic steroid antimicrobials (CSAs), are synthetically produced small molecule chemical compounds consisting of a sterol backbone with amino acids and other chemical groups attached to them. These compounds have a net positive charge that is electrostatically attracted to the negatively charged cell membranes of certain viruses, fungi and bacteria. CSAs have a high binding affinity for such membranes (including Lipid A) and are able to rapidly disrupt the target membranes leading to rapid cell death. While CSAs have a mechanism of action that is also seen in antimicrobial peptides, which form part of the body's innate immune system, they avoid many of the difficulties associated with their use as medicines.

Ceragenins were invented by Dr. Paul B. Savage of Brigham Young University's Department of Chemistry and Biochemistry. In data previously presented by Dr. Savage and other researchers, CSAs have been shown to have broad spectrum antibacterial activity. Dr. Derya Unutmaz, Associate Professor of Microbiology and Immunology at the Vanderbilt University School of Medicine, tested several CSAs in his laboratory for their ability to kill HIV directly. According to Unutmaz, "We have some preliminary but very exciting results. But we would like to formally show this before making any claims that would cause unwanted hype."

Lac-des-Îles Water Aerodrome

Lac-des-Îles Water Aerodrome, (TC LID: CSA9), was located on Lac-des-Îles, Quebec, Canada and is open from May until November.

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Airó

Airó is a Portuguese parish, located in the municipality of Barcelos. The population in 2011 was 913, in an area of 3.02 km².

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Air (classical element)

Air (also sometimes called Wind) is often seen as a universal power or pure substance. Its fundamental importance to life can be seen in words such as aspire, inspire, perspire and spirit, all derived from the Latin spirare.

Greek and Roman tradition

Air is one of the four classical elements in ancient Greek philosophy and science. According to Plato, it is associated with the octahedron; air is considered to be both hot and wet. The ancient Greeks used two words for air: aer meant the dim lower atmosphere, and aether meant the bright upper atmosphere above the clouds.Plato, for instance writes that "So it is with air: there is the brightest variety which we call aether, the muddiest which we call mist and darkness, and other kinds for which we have no name...." Among the early Greek Pre-Socratic philosophers, Anaximenes (mid-6th century BCE) named air as the arche. A similar belief was attributed by some ancient sources to Diogenes Apolloniates (late 5th century BCE), who also linked air with intelligence and soul (psyche), but other sources claim that his arche was a substance between air and fire.Aristophanes parodied such teachings in his play The Clouds by putting a prayer to air in the mouth of Socrates.

Air (Agua de Annique album)

Air is the debut album of the band Agua de Annique formed by the former The Gathering vocalist Anneke van Giersbergen. The album is a pop/rock oriented album and was released in 2007. Anneke van Giersbergen also plays piano on the album.

Track listing

All tracks by Anneke van Giersbergen except where noted

There is an animated video of the song "Day After Yesterday" which can be viewed on their official site. There is also a video for the cover song "Come Wander With Me," which was released as a download-single in 2008.

Personnel

External links