COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial, also known as coenzyme Q9 homolog (COQ9), is a protein that in humans is encoded by the COQ9 gene.
Function
This locus represents a mitochondrial ubiquinone biosynthesis gene. The encoded protein is likely necessary for biosynthesis of coenzyme Q10, as mutations at this locus have been associated with autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency.
Clinical significance
It may be associated with Coenzyme Q10 deficiency.
Model organisms
Model organisms have been used in the study of COQ9 function. A conditional knockout mouse line, called Coq9tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty two tests were carried out on homozygous mutant mice and one significant abnormality was observed: females displayed hyperactivity in an open field test.
Podcasts:
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by C21
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by Q65
-
by K-7
-
by K-7
-
by K-7
All That I Want
by: C21ALL THAT I WANT / C21
I just need you to know
That everytime you walk into a room I get a feeling
And I try to make it show
But every now and then it seems as though you don't believe it
Girl just dance
I like the way you move it
Just shake, shake, shake into the music
C'mon and dance
Don't worry about it
Don't need to play no games 'cause I love you just the same
(You turn) me on and on turn me on
The definition of all that I want
But you don't seem to hear me at all
I'm telling you
Baby you're all that I want
All that I want
All that I know
is your the only one that makes me feel the way you do girl
And time will show
That all this jealousy is just a waste of emotion
Girl just dance
I like the way you move it
Just shake, shake, shake into the music
C'mon and dance
Don't worry about it
Don't need to play no games 'cause I love you just the same
(You turn) me on and on turn me on
The definition of all that I want
But you don't seem to hear me at all
I'm telling you
Baby you're all that I want
All that I want
Just hear me now
I want you to know
I'm into you
And you alone
Just hear me now
I want you to know
I'm into you
And you alone
Girl just dance
I like the way you move it
Just shake, shake, shake into the music
C'mon and dance
Don't worry about it
Don't need to play no games 'cause I love you just the same
(You turn) me on and on turn me on
The definition of all that I want
But you don't seem to hear me at all
I'm telling you
Baby you're all that I want
(You) turn me on and on turn me on
The definition of all that I want
But you don't seem to hear me at all
I'm telling you
Baby you're all that I want
You're turning me on girl
C'mon and just dance girl
You're making me sweat girl