COPS6
COP9 signalosome complex subunit 6 is a protein that in humans is encoded by the COPS6 gene.
Function
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Interactions
COPS6 has been shown to interact with EIF3S6.
References
Further reading
Podcasts:
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by Jimi Hendrix
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by Cave-In
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by Nightingale
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by Dream Academy
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by Handguns
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by Bug Mafia
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by Karen O & The Kids
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by Ephemera
Gypsy Eyes
by: Jimi HendrixWell I realize that I've been hypnotized,
I love your gypsy eyes
I love your gypsy eyes
Alright!
Hey!
Gypsy.
Way up in my tree I'm sitting by my fire
Wond'rin' where in this world might you be
And knowin' all the time you're still roamin' in the country side
Do you still think about me?
Oh my gypsy.
Well I walked right on to your rebel roadside
The one that rambles on for a million miles
Yes I walk down this road searchin' for your love and ah my soul too
But when I find ya I ain't gonna let go.
I remember the first time I saw you
The tears in your eyes look like they're tryin' to say
Oh little boy you know I could love you
But first I must make my get away
Two strange men fightin' to the death over me today
I'll try to meet cha by the old highway.
Hey!
Well I realize that I've been hypnotized, I love your gypsy eyes
I love your gypsy eyes
I love your gypsy eyes
I love your gypsy eyes
Alright!
I've been searchin' so long my feet have made me lose the battle
Down against the road my weary knees they got me
Off to the side I fall but I hear a sweet call
My gypsy eyes is comin' and I've been saved.
Oh I've been saved
That's why I love you uh
Said I love you
Hey!
Love you uh
Lord I love you