Collagen alpha-1(XI) chain is a protein that in humans is encoded by the COL11A1 gene.
The COL11A1 gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Three transcript variants encoding different isoforms have been identified for this gene.
Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome.
Stickler syndrome, type II is an autosomal dominant condition caused by a mutation in the COL11A1 gene. Features of Stickler syndrome type II include: sensorineural hearing loss, facial features (flat facial profile, anteverted nares, micrognathia), cleft palate, visual disturbances (type 2 vitreous anomaly, childhood-onset myopia, glaucoma, cataracts and retinal detachment), spondyloepiphyseal dysplasia, and arthropathy.
Tired of looking at your photographs
Smiling at your latest craze
You can change the things you say and do
But nothing can change the fact
That you are sadly deranged
And i want nothing to do with you
No more hot tears and pride
No more bloodshed this time
I’m moving on to a better place
Nightmares don’t arrive when i see your face
Cannot hold on to a bitter past
Candles like us were never meant to last
Maybe you were right and i was wrong
But nonetheless this is my final song
About you
Tired of thinking about memories
Laughing at your plastic head
Even after all that we’ve been through
Nothing can change the fact
That i walked the path
And i was happy to see it through
No more hot tears and pride
No more bloodshed this time
I’m moving on to a better place
Nightmares don’t arrive when i see your face
Cannot hold on to a bitter past
Candles like us were never meant to last
Maybe you were right and i was wrong
But nonetheless this is my final song
Let’s go…
Maybe you were right and i was wrong
But nonetheless this is my final song
Maybe you were right and i was wrong
But nonetheless this is my final song
I’m moving on to a better place
Nightmares don’t arrive when i see your face
Cannot hold on to a bitter past
Candles like us were never meant to last
Maybe you were right and i was wrong