CLIC4

Chloride intracellular channel 4, also known as CLIC4, is a eukaryotic gene.

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).

Binding partners

CLIC4 binds to dynamin I, α-tubulin, β-actin, creatine kinase and two 14-3-3 isoforms.

See also

  • Chloride channel
  • References

    Further reading

    External links

  • CLIC4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
  • This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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