CHD4

Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene.

Function

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.

Interactions

CHD4 has been shown to interact with HDAC1,Histone deacetylase 2,MTA2,SATB1 and Ataxia telangiectasia and Rad3 related.

References

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Why Do Lovers Break Each Others Hearts

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Why Do Lovers Break Each Others Hearts

by: Showaddywaddy

Why do lovers break each others hearts?
Oh, tell me why do lovers have to drift apart,
When we met the world was right,
Now I'm crying every night,
Why do lovers break each others hearts?
Why do lovers break each others hearts?
Oh, tell me why can't lovers finish what they start,
A year ago we were one,
Now just look at what we've done,
Why do lovers break each others hearts?
Help me, help me, I don't understand,
Why we always hurt the ones we love.
Tell me, tell me where's the life we planned,
Where are the dreams ,
That we dream we're dreaming oh-oh-oh-of?
Why do lovers break each others hearts?
Oh, tell me why do lovers have to drift apart,
When we met the world was right,
Now I'm crying every night,
Why do lovers break each others hearts? (Instrumental)
When we met the world was right,
Now I'm crying every night,
Why do lovers break each others hearts,
Why do lovers break each others hearts?