CGP-7930

CGP-7930 is a compound used in scientific research which acts as a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists such as baclofen and GHB, as well as reducing self-administration of ethanol and cocaine.

References


CGP 52608

CGP 52608 is a selective ligand of the RAR-related orphan receptor alpha. CGP 52608 has also been reported to possess antiarthritic activity.

CGP 52608 contains a thiazolinidinedione group.


References

External links

  • CGP 52608 at the US National Library of Medicine Medical Subject Headings (MeSH)
  • CGP-37849

    CGP-37849 is a competitive antagonist at the NMDA receptor. It is a potent, orally active anticonvulsant in animal models, and was researched for the treatment of epilepsy. It also has neuroprotective activity and shows antidepressant and anxiolytic effects.


    References

  • Fagg GE, Olpe HR, Pozza MF, Baud J, Steinmann M, Schmutz M, Portet C, Baumann P, Thedinga K, Bittiger H, et al. CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activity. British Journal of Pharmacology. 1990 Apr;99(4):791-7. PMID 1972895
  • Schmutz M, Portet C, Jeker A, Klebs K, Vassout A, Allgeier H, Heckendorn R, Fagg GE, Olpe HR, van Riezen H. The competitive NMDA receptor antagonists CGP 37849 and CGP 39551 are potent, orally-active anticonvulsants in rodents. Naunyn-Schmiedebergs Archives of Pharmacology. 1990 Jul;342(1):61-6. PMID 1976233
  • Fujikawa DG, Daniels AH, Kim JS. The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage. Epilepsy Research. 1994 Mar;17(3):207-19. PMID 7912191
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