CFTR is a radio station serving the Greater Toronto Area. Owned by Rogers Media, it broadcasts an all-news format branded as 680 NEWS. CFTR's studios are located at the Rogers Building at Bloor and Jarvis in downtown Toronto, while its 8-tower transmitter array is located on the southern edge of Lake Ontario at Oakes and Winston Road (near the QEW and Casablanca Road) in Grimsby.
The station launched in 1962 on 1540 kHz as CHFI-AM, simulcasting the beautiful music of CHFI-FM, one of Canada's first FM radio stations. Since 1540 was a clear-channel frequency assigned to stations in the United States and the Bahamas, CHFI-AM was authorized to broadcast only during the daytime. In 1963, it sought to pay CHLO in St. Thomas, Ontario to move from 680 to another frequency to free up 680 for CHFI-AM's use. No deal was finalized, but, by 1966, the stations reached an agreement to share 680, and CHFI-AM moved to twenty-four hour operation at that frequency.
In 1971, it changed its call letters to CFTR, a tribute to Ted Rogers, Sr., radio pioneer and father of controlling shareholder Ted Rogers.
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.
CFTR is an ABC transporter-class ion channel that codes for a protein that conducts chloride and thiocyanate ions across epithelial cell membranes. Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial fluid transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens and epididymis appear to result from abnormal intraluminal secretions, causing congenital absence of the vas deferens and male infertility.
CFTR may refer to: