Fas receptor
The FAS receptor (FasR), also known as apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6) is a protein that in humans is encoded by the TNFRSF6 gene.
The Fas receptor is a death receptor on the surface of cells that leads to programmed cell death (apoptosis). It is one of two apoptosis pathways, the other being the mitochondrial pathway. FasR is located on chromosome 10 in humans and 19 in mice. Similar sequences related by evolution (orthologs) are found in most mammals.
Gene
FAS receptor is located on the long arm of chromosome 10 (10q24.1) in humans and on chromosome 19 in mice. The gene lies on the plus (Watson strand) and is 25,255 bases in length organised into 9 protein encoding exons.
Protein
Previous reports have identified as many as eight splice variants, which are translated into seven isoforms of the protein. Apoptosis-inducing Fas receptor is dubbed isoform 1 and is a type 1 transmembrane protein. Many of the other isoforms are rare haplotypes that are usually associated with a state of disease. However, two isoforms, the apoptosis-inducing membrane-bound form and the soluble form, are normal products whose production via alternative splicing is regulated by the cytotoxic protein TIA1.
Podcasts:
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Keith Sweat
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by Kidd Video
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by Kidd Video
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by Kidd Video
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by Kidd Video
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by Kidd Kidd
YOU GOT ME
by: Keith Sweat[Lox]
Uh, yeah, uh huh, yeah
Yeah, yeah, yeah, uh huh, yeah, yeah
It's another one
Uh huh, yeah, yeah
It's another one, and another one
You got me where you want me
You could listen to Levert while leaving the country
And then sweat it out when you feel comfy
Or play Gill to the minute that ou say you're hungry
Uh, you got me where you want me
You could listen to Levert while leaving the country
And then sweat it out when you're feeling comfy
Or play gill to the minute that you say you're hungry
Uh, you got me where you want me
You could listen to Levert while leaving the country
And then Sweat it out when your'e feeling comfy
Or play Gill to the minute that you say you're hungry
[LSG]
I know
You need
Love and understanding
Sometimes
Feel like
I can't give you more of my time
You keep on wanting me
To be there girl
But I can't be
Why you keep stressing me
When you know I'm doing my best
I keep on telling you
I do the best that I can do
How can I get through to you
Everything I do is for you
1 - You got me where you want me
Tell me what you need
Take me baby
Tell me what you want
Anywhere you wanna go is for me
You got me where you want me
I can't keep on going through these changes
The more you doubt me
You keep pusing me away girl
You keep on wanting more
I'm doing my best
I'm doing everything for you
Repeat 1
Girl, you got me yearning
Yearning to know what I'll do with love
Can you tell me what I'm doing
But I'm always saying you don't understand
I'll never leave you alone
Repeat 1
Repeat Lox