CD64

CD64 can refer to:

CD64 (Nintendo)

The CD64 is a game backup device made by UFO/Success Company for the Nintendo 64 that allows to run ROM files off a CD-ROM attached to the system. Similar to the Doctor V64 and the Z64 units for the N64, it is most commonly used for playing backups of Nintendo 64 games. Since it has a built-in communications port that is accessible from the N64 program, it can also be used as a rather versatile development/debug device.

Design

The CD64 sits underneath the N64 unit, making use of the EXTension port on the bottom of the console. Once connected and plugged in, a game cartridge is taken out of the N64 and one is placed into the slot on the face of the system, just underneath the N64 and just above the CD-ROM drive, to act as a kind of boot disk.

When the unit is turned on, via the N64 power button, a GUI is shown where you can choose to launch the game in the slot, or run the ROM file on the CD in the CD-ROM. The ROM file is loaded into the PC RAM found within the system.

The first version of the unit was solid black, like the N64 itself, and had only 128Mb of RAM. While upgradeable, the RAM was usually glued into place with a hot glue gun. The second version, known as the CD64+ (or 'Plus') was apparently more stable than the first and was transparent grey. This unit came with 256Mb installed, again glued in place, but still capable of being upgraded.

CD64 (biology)

CD64 (Cluster of Differentiation 64) is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity. It is more commonly known as Fc-gamma receptor 1 (FcγRI). After binding IgG, CD64 interacts with an accessory chain known as the common γ chain (γ chain), which possesses an ITAM motif that is necessary for triggering cellular activation.

Structurally CD64 is composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail.

CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

There are three distinct (but highly similar) genes in humans for CD64 called FcγRIA (CD64A), FcγRIB (CD64B), and FcγRIC (CD64C) that are located on chromosome 1. These three genes produce six different mRNA transcripts ; two from CD64A, three from CD64B, and one from CD64C; by alternate splicing of the genes.