CD37

Leukocyte antigen CD37 is a protein that in humans is encoded by the CD37 gene.

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

See also

  • Cluster of differentiation

    • References

    Further reading

    External links

  • CD37 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

    • This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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