CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene.
CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication.
[Verse:]
He gave his baby boy a bath
Tub full of bubbles and toys for him to splash
Look at daddy, soapsuds mustache
Funny faces and voices, it makes the baby belly laugh
Dry him off, now you squeaky clean
And watch the water spiral down that drain
Wrap him in a towel so he doesn't get the shivers
Brush his hair, it seems to help it dry it quicker
Laid him on mommy and daddy's bed now that he's dry
And put a diaper on him, gave him his pacifier
Superman pajamas, so tough
Innocent face full of unconditional love
Daddy picked him and rocked him slow
Never takes long for little guy's eyes to close
Dad's technique is different than your mother's
Never learned any lullabies, he sings Stevie Wonder's
There it is, steady breathing, sleep rhythm
Daddy sits and holds him just to listen for a minute
Daddy's hands are the meaning of security
And baby's hands are the evidence of purity
Thinking back to the day baby came
And how it changed the whole game, things ain't the same
Daddy had to stop running it crazy
Keep his ass in the home with the son and his lady
He was there for the birth and the first breath
Not gonna miss the first words or the first steps
Gonna keep the boy healthy and safe
And do his best to try to keep those tears off his face
Gave him a kiss, laid him in his crib
Turned out the lights, goodnight my little prince
That's how good daddy takes care of him