C2orf27

Uncharacterized protein C2orf27 is a protein that in humans is encoded by the C2orf27A gene. Although its function is not clearly understood, through the use of bioinformatic analysis more information is being brought to light.

Gene

The mRNA is 1,222bp in length and is located at 2q21.2 with a total of five exons in Homo sapiens. Other sources list C2orf27B as a paralog but this is unlikely due the fact that the locations of both genes are in the same place on chromosome 2. It seems to be generally accepted that they are the same gene. Other gene aliases include C2orf27 and chromosome 2 open reading frame 27A. The gene is surrounded upstream by POTEKP and downstream by ANKRD30BL.

Protein

The length of the C2orf27 protein sequence is 203 a.a. in length and has a molecular weight of 21.5 kDa with a pI of 5.13 in Homo sapiens. When taking into account the primate orthologs, the molecular weights range from 21.4 to 36.7 kDa with the isoelectric point ranging from 4.58 to 5.25. This gene is located in the nucleus of the cell and, it doesn't contain any transmembrane regions.