Bruno is a comune (municipality) in the Province of Asti in the Italian region Piedmont, located about 70 kilometres (43 mi) southeast of Turin and about 20 kilometres (12 mi) southeast of Asti. As of 31 December 2004, it had a population of 379 and an area of 9.2 square kilometres (3.6 sq mi).
Bruno borders the following municipalities: Bergamasco, Carentino, Castelnuovo Belbo, and Mombaruzzo.