San Giacomo (Italian for Saint James) may refer to a number of churches and settlements (usually named after churches), including:
San Giacomo is a mountain village in the Province of Teramo in the Abruzzo region of Italy. It is a frazione of the comune of Valle Castellana.
San Giacomo lies at an altitude of 1105 m, within the Gran Sasso e Monti della Laga National Park. The town takes its name from the presence of an ancient building, belonging to the monastery of San Giacomo, which once sat at a slightly lower elevation. This building served as a refuge for workers who once tilled the landholdings in the area that belonged to the church. One ridge in this area still carries the name Costa del prevosto (Ridge of the Provost) in reference to this fact.
San Giacomo is situated on the border of the Italian regions of Abruzzo and Marche. Prior to the formation of the united Italy in 1861, this land served at the point of demarcation between the Kingdom of Two Sicilies and the Vatican State.
One marker stone dated 1847 identifies a boundary, probably first delineated by Ruggiero II in the twelfth century, dividing the holdings of the leaders of Rome with those of the Neapolitans. The remains of several customs checkpoints have also been unearthed nearby. At one point they likely served to control the passage of contraband between these two rival states. These checkpoints in turn were likely built on the remains of a still older Catholic hermitage. German soldiers made use of this area in the latter part of World War II as they fought their losing battles against the local Italian partisan forces.